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Master of Public Health

Damage control laparotomy trial: design, rationale and implementation of a randomized controlled trial.

AUTHORS

Harvin JA , Podbielski J , Vincent LE , Fox EE , Moore LJ , Cotton BA , Wade CE , Holcomb JB , . Trauma surgery & acute care open. 2017 1 1; 2(1). e000083

ABSTRACT

Damage control laparotomy (DCL) is an abbreviated operation intended to prevent the development of hypothermia, acidosis, and coagulopathy in seriously injured patients. The indications for DCL have since been broadened with no high-quality data to guide treatment. For patients with an indication for DCL, we aim to determine the effect of definitive laparotomy on patient morbidity.

Damage control laparotomy (DCL) is an abbreviated operation intended to prevent the development of hypothermia, acidosis, and coagulopathy in seriously injured patients. The indications for DCL have since been broadened with no high-quality data to guide treatment. For patients with an indication for DCL, we aim to determine the effect of definitive laparotomy on patient morbidity.

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