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Master of Public Health

Effect of previous year vaccination on the efficacy, immunogenicity, and safety of high-dose inactivated influenza vaccine in older adults.

AUTHORS

DiazGranados CA , Dunning AJ , Robertson CA , Talbot HK , Landolfi V , Greenberg DP , . Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2016 2 21; ().

ABSTRACT

 high-dose inactivated influenza vaccine (IIV-HD) is an alternative to the standard-dose inactivated influenza vaccine (IIV-SD) in the US for influenza prevention in older adults. IIV-HD improved efficacy relative to IIV-SD in a randomized controlled trial. Recent observational studies suggest that previous influenza vaccination may influence the immunogenicity and effectiveness of current-season vaccination.

 high-dose inactivated influenza vaccine (IIV-HD) is an alternative to the standard-dose inactivated influenza vaccine (IIV-SD) in the US for influenza prevention in older adults. IIV-HD improved efficacy relative to IIV-SD in a randomized controlled trial. Recent observational studies suggest that previous influenza vaccination may influence the immunogenicity and effectiveness of current-season vaccination.

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