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Master of Public Health

Evaluating the case-positive, control test-negative study design for influenza vaccine effectiveness for the frailty bias.

AUTHORS

Talbot HK , Nian H , Chen Q , Zhu Y , Edwards KM , Griffin MR , . Vaccine. 2016 2 28; ().
  • NIHMSID: 8406899

ABSTRACT

Previous influenza vaccine effectiveness studies were criticized for their failure to control for frailty. This study was designed to see if the test-negative study design overcomes this bias.

Previous influenza vaccine effectiveness studies were criticized for their failure to control for frailty. This study was designed to see if the test-negative study design overcomes this bias.

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