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Master of Public Health

Future Research Directions in Asthma: An NHLBI Working Group Report.

AUTHORS

Levy BD , Noel PJ , Freemer MM , Cloutier MM , Georas SN , Jarjour NN , Ober C , Woodruff PG , Barnes KC , Bender BG , Camargo CA , Chupp GL , Denlinger LC , Fahy JV , Fitzpatrick AM , Fuhlbrigge A , Gaston BM , Hartert TV , Kolls JK , Lynch SV , Moore WC , Morgan WJ , Nadeau KC , Ownby DR , Solway J , Szefler SJ , Wenzel SE , Wright RJ , Smith RA , Erzurum SC , . American journal of respiratory and critical care medicine. 2015 8 25; ().

ABSTRACT

Asthma is a common chronic disease without cure. Our understanding of asthma onset, pathobiology, classification and management has evolved substantially over the past decade; however, significant asthma-related morbidity and excess healthcare utilization and cost persist. To address this important clinical condition, the National Heart, Lung, and Blood Institute (NHLBI) convened a group of extramural investigators for an Asthma Research Strategic Planning workshop on September 18-19, 2014 to accelerate discoveries and their translation to patients. The workshop focused on (1) in utero and early life origins of asthma, (2) the use of phenotypes and endotypes to classify disease, (3) defining disease modification, (4) disease management, and (5) implementation research. This report summarizes the workshop, producing recommendations to guide future research in asthma.

Asthma is a common chronic disease without cure. Our understanding of asthma onset, pathobiology, classification and management has evolved substantially over the past decade; however, significant asthma-related morbidity and excess healthcare utilization and cost persist. To address this important clinical condition, the National Heart, Lung, and Blood Institute (NHLBI) convened a group of extramural investigators for an Asthma Research Strategic Planning workshop on September 18-19, 2014 to accelerate discoveries and their translation to patients. The workshop focused on (1) in utero and early life origins of asthma, (2) the use of phenotypes and endotypes to classify disease, (3) defining disease modification, (4) disease management, and (5) implementation research. This report summarizes the workshop, producing recommendations to guide future research in asthma.

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