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Master of Public Health

Impact of blood products on platelet function in patients with traumatic injuries: a translational study.

AUTHORS

Henriksen HH , Grand AG , Viggers S , Baer LA , Solbeck S , Cotton BA , Matijevic N , Ostrowski SR , Stensballe J , Fox EE , Chen TA , Holcomb JB , Johansson PI , Cardenas JC , Wade CE , . The Journal of surgical research. 2017 6 15; 214(). 154-161

ABSTRACT

Reductions in platelet (PLT) count and function are associated with poor outcomes in trauma patients. We proposed to determine if patients expected to receive blood products have a decrease in PLT function higher than expected based on the reduction in PLT count, and if the reduction in function could be associated with the donor plasma/supernatant received.

Reductions in platelet (PLT) count and function are associated with poor outcomes in trauma patients. We proposed to determine if patients expected to receive blood products have a decrease in PLT function higher than expected based on the reduction in PLT count, and if the reduction in function could be associated with the donor plasma/supernatant received.

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