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Master of Public Health

Improvements in Antimicrobial Prescribing and Outcomes in Pediatric Complicated Appendicitis.

AUTHORS

Willis ZI , Duggan EM , Gillon J , Blakely ML , Di Pentima MC , . The Pediatric infectious disease journal. 2017 10 28; ().

ABSTRACT

Complicated appendicitis, characterized by perforation and/or peritonitis, is common in children, and late infectious complications are frequent. The best antibiotic treatment approach is unknown, resulting in substantial variation in care. We evaluated the effects of two successive interventions, an antimicrobial stewardship program (ASP) and a condition-specific clinical practice guideline (CPG), on antimicrobial utilization and patient outcomes in these patients.

Complicated appendicitis, characterized by perforation and/or peritonitis, is common in children, and late infectious complications are frequent. The best antibiotic treatment approach is unknown, resulting in substantial variation in care. We evaluated the effects of two successive interventions, an antimicrobial stewardship program (ASP) and a condition-specific clinical practice guideline (CPG), on antimicrobial utilization and patient outcomes in these patients.

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