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Master of Public Health

Non-interference of rotavirus vaccine with measles-rubella vaccine at 9 months and improvements in anti-rotavirus immunity: a randomized trial.

AUTHORS

Zaman K , Fleming JA , Victor JC , Yunus M , Bari TI , Azim T , Rahman M , Mowla SM , Bellini WJ , McNeal M , Icenogle JP , Lopman B , Parashar U , Cortese MM , Steele AD , Neuzil KM , . The Journal of infectious diseases. 2016 1 27; ().

ABSTRACT

 The burden of rotavirus morbidity and mortality is high in children under 5 years in developing countries and evaluations indicate waning protection from rotavirus immunization in the second year. An additional dose of rotavirus vaccine may enhance the immune response and lengthen the period of protection against disease, however co-administration should not interfere with immune responses to concurrently given vaccines.

 The burden of rotavirus morbidity and mortality is high in children under 5 years in developing countries and evaluations indicate waning protection from rotavirus immunization in the second year. An additional dose of rotavirus vaccine may enhance the immune response and lengthen the period of protection against disease, however co-administration should not interfere with immune responses to concurrently given vaccines.

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