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Master of Public Health

Pneumococcal Community-Acquired Pneumonia Detected by Serotype-Specific Urinary Antigen Detection Assays.

AUTHORS

Wunderink RG , Self WH , Anderson EJ , Balk R , Fakhran S , Courtney DM , Qi C , Williams DJ , Zhu Y , Whitney CG , Moore MR , Bramley A , Jain S , Edwards KM , Grijalva CG , . Clinical infectious diseases : an official publication of the Infectious Diseases Society of America. 2018 1 12; ().
  • NIHMSID: 9203213

ABSTRACT

Streptococcus pneumoniae is considered the leading bacterial cause of pneumonia in adults. Yet, it was not commonly detected by traditional culture-based and conventional urinary testing in a recent multicenter etiology study of adults hospitalized with community-acquired pneumonia (CAP). We used novel serotype-specific urinary antigen detection (SSUAD) assays to determine whether pneumococcal cases were missed by traditional testing.

Streptococcus pneumoniae is considered the leading bacterial cause of pneumonia in adults. Yet, it was not commonly detected by traditional culture-based and conventional urinary testing in a recent multicenter etiology study of adults hospitalized with community-acquired pneumonia (CAP). We used novel serotype-specific urinary antigen detection (SSUAD) assays to determine whether pneumococcal cases were missed by traditional testing.

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