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Serum Fatty Acids Are Correlated with Inflammatory Cytokines in Ulcerative Colitis.


AUTHORS

Wiese DM , Horst SN , Brown CT , Allaman MM , Hodges ME , Slaughter JC , Druce JP , Beaulieu DB , Schwartz DA , Wilson KT , Coburn LA , . PloS one. 2016 1 1; 11(5). e0156387

ABSTRACT

Ulcerative colitis (UC) is associated with increased dietary intake of fat and n-6 polyunsaturated fatty acids (PUFA). Modification of fat metabolism may alter inflammation and disease severity. Our aim was to assess differences in dietary and serum fatty acid levels between control and UC subjects and associations with disease activity and inflammatory cytokines.


Ulcerative colitis (UC) is associated with increased dietary intake of fat and n-6 polyunsaturated fatty acids (PUFA). Modification of fat metabolism may alter inflammation and disease severity. Our aim was to assess differences in dietary and serum fatty acid levels between control and UC subjects and associations with disease activity and inflammatory cytokines.


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