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Statin therapy reduces plasma endothelin-1 concentrations: A meta-analysis of 15 randomized controlled trials.


AUTHORS

Sahebkar A , Kotani K , Serban C , Ursoniu S , Mikhailidis DP , Jones SR , Ray KK , Blaha MJ , Rysz J , Toth PP , Muntner P , Lip GY , Banach M , , . Atherosclerosis. 2015 6 3; 241(2). 433-442

ABSTRACT

Raised plasma endothelin-1 (ET-1) levels may be a risk factor for vascular dysfunction and cardiovascular (CV) disease. This meta-analysis assessed the effect of statins on circulating ET-1 concentrations.


Raised plasma endothelin-1 (ET-1) levels may be a risk factor for vascular dysfunction and cardiovascular (CV) disease. This meta-analysis assessed the effect of statins on circulating ET-1 concentrations.


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