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Master of Public Health

Urogenital Manifestations of Metastatic Crohn's Disease in Children: Case Series and Review of the Literature.

AUTHORS

Rani U , Russell A , Tanaka S , Correa H , Nicholson M , . Urology. 2016 2 24; ().

ABSTRACT

Although cutaneous manifestations are the most common extraintestinal manifestation of inflammatory bowel disease, metastatic Crohn’s disease (MCD) is rare. MCD is defined as the presence of non-caseating granulomatous inflammation and perivascular infiltrate in the cutaneous tissue that is non-contiguous to the gastrointestinal tract. MCD rarely involves the genitourinary tract in children. When it does, it can present as external genitalia swelling, erythema, plaques or ulcerations. Here we present three pediatric cases of MCD involving the genitourinary tract. In addition to discussion of the presented cases, we have reviewed the literature on the genitourinary presentation of MCD in the pediatric population.

Although cutaneous manifestations are the most common extraintestinal manifestation of inflammatory bowel disease, metastatic Crohn’s disease (MCD) is rare. MCD is defined as the presence of non-caseating granulomatous inflammation and perivascular infiltrate in the cutaneous tissue that is non-contiguous to the gastrointestinal tract. MCD rarely involves the genitourinary tract in children. When it does, it can present as external genitalia swelling, erythema, plaques or ulcerations. Here we present three pediatric cases of MCD involving the genitourinary tract. In addition to discussion of the presented cases, we have reviewed the literature on the genitourinary presentation of MCD in the pediatric population.

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