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Master of Public Health

Utility of Non-Traditional Risk Markers in Individuals Ineligible for Statin Therapy According to the 2013 ACC/AHA Cholesterol Guidelines.

AUTHORS

Yeboah J , Polonsky TS , Young R , McClelland RL , Delaney JC , Dawood F , Blaha MJ , Miedema MD , Sibley CT , Carr JJ , Burke GL , Goff DC , Psaty BM , Greenland P , Herrington DM , . Circulation. 2015 7 29; ().

ABSTRACT

-In the general population, the majority of cardiovascular events occur in people at the low to moderate end of population risk distribution. The 2013 American College of Cardiology/ American Heart Association guideline on the treatment of blood cholesterol recommends consideration of statin therapy for adults with an estimated 10-year atherosclerotic cardiovascular disease (ASCVD) risk ≥7.5% based on traditional risk factors. Whether use of non-traditional risk markers can improve risk assessment in those below this threshold for statin therapy is unclear.

-In the general population, the majority of cardiovascular events occur in people at the low to moderate end of population risk distribution. The 2013 American College of Cardiology/ American Heart Association guideline on the treatment of blood cholesterol recommends consideration of statin therapy for adults with an estimated 10-year atherosclerotic cardiovascular disease (ASCVD) risk ≥7.5% based on traditional risk factors. Whether use of non-traditional risk markers can improve risk assessment in those below this threshold for statin therapy is unclear.

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