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The lab of Lauren Jackson provides the first evidence of an endosomal “supercomplex” and reveals a vital role for VARP in mediating coat assembly in a recent paper published in Science Advances. Read More

People are complicated and so it should be no surprise that among the most difficult tasks that you’ll face as a research group leader in science is recruiting and successfully managing talented and collegial students, postdocs, and staff. This may be especially true for assistant professors and their peers in industry or at research institutes. Read More

If there is any chance that you will eventually want to apply for a MIRA/R35 award from a particular institute, you should think twice about submitting an MPI grant to that institute, as this may limit your options several years down the road. Read More

Doug Kojetin, associate professor of biochemistry, and a collaborator from the Guangzhou Laboratory, use NMR and crystallography to elucidate the binding pose of GW9662 and T0070907 cobound with synthetic ligands for the first time. Read More

For more than 50 years, Vanderbilt has been a global leader in the quest to understand, prevent, and treat diabetes. Read More

There's a tendency to view the past as a "failed" state, assuming that evolution drives toward optimization. This isn't necessarily true. There is a vast, complex history we have yet to fully understand—and we should strive to uncover it. Read More

The Center for Extracellular Vesicle Research, which is made up of over 20 laboratories spanning Vanderbilt University, held its annual retreat in late September. Researchers discussed the types of biomolecular cargoes EVs contain and how EVs holding unique cargoes can be used as diagnostic tools. Read More

Polycystic ovarian syndrome  is a complex endocrinological disorder with widespread prevalence, affecting approximately one in ten women worldwide. Treatment for PCOS typically involves extensive lifestyle modification and medications to help manage reproductive symptoms and insulin resistance, but there are no treatments that directly target hyperandrogenism. Because of this, women with PCOS often feel unsatisfied with the quality of their care and are belabored by the changes necessary to live out their daily lives. Read More

By Chuck Sanders When I was 13, my brother Scott (12) and I joined our neighbors Matha (12) and Jay (10) on a trip to their family cottage on the bank of the Allegheny River in western Pennsylvania. I had fantasized about this trip for months; I… Read More