Research, News & Discoveries

by Marissa Shapiro Apr. 13, 2021, 9:00 AM Pioneering research from Vanderbilt scientists shows that cells respond differently to acute stress than to gradual stress. The findings establish an entirely new way to look at cell-to-cell communication, or signaling, and may fundamentally change how… Read More

Apr. 9, 2021, 8:00 AM Alissa Guarnaccia, Ph.D. in cell and developmental biology, School of Medicine Basic Sciences (Vanderbilt University) Alissa Guarnaccia is jumping into a highly sought-after research career to help find treatments for cancer at the cellular level. But lately she’s taking time to write lots of thank-you… Read More

Apr. 8, 2021, 8:55 AM by Bill Snyder Cancer specialists at Vanderbilt University Medical Center, in partnership with biochemists and structural biologists across the Vanderbilt University campus, are taking “personalized” cancer therapy to a new level. Benjamin Brown, left, Jens Meiler, PhD, Zhenfang Du, PhD, and colleagues are studying the… Read More

by Ann Marie Deer Owens Apr. 8, 2021, 1:30 PM Dr. James Crowe Jr., professor of medicine, in his lab at Medical Research Building IV. (John Russell/Vanderbilt University) Dr. James E. Crowe Jr., a physician-scientist on the front lines of global research… Read More

Apr. 7, 2021, 10:00 AM From left, Kimryn Rathmell, MD, PhD, Bradley Reinfeld, Matthew Madden and Jeffrey Rathmell, PhD, have discovered that immune cells — not cancer cells — are the major glucose consumers in the tumor microenvironment, upending a century-old observation. (photo by Susan Urmy) by Leigh MacMillan Tumors… Read More

The Joe B. Wyatt Distinguished University Professor Award, established in honor of Chancellor Joe B. Wyatt upon his retirement in 2000, recognizes faculty accomplishments that span multiple academic disciplines. Denison, Edward Claiborne Stahlman Professor of Pediatric Physiology and Cell Metabolism and one of the world’s foremost experts on coronaviruses,… Read More

Apr. 1, 2021, 11:00 AM by Bill Snyder Rift Valley Fever Virus (RVFV) is an emerging infection in sub-Saharan and North Africa that causes severe, hemorrhagic illness in livestock and humans and which has pandemic potential. James Crowe Jr., MD, and colleagues isolated a panel of human monoclonal antibodies from… Read More

Apr. 1, 2021, 9:33 AM Deanna Edwards, PhD, left, Jin Chen, MD, PhD, and colleagues are studying a new therapeutic strategy for triple-negative breast cancer. (photo by Donn Jones) by Leigh MacMillan Triple-negative breast cancer cells engage in a “glutamine steal” — outcompeting T cells for the nutrient glutamine and… Read More

Apr. 1, 2021, 9:23 AM   by Bill Snyder Despite an impressive vaccination effort that exceeds 2 million shots a day, rates of COVID-19 are again on the rise in several parts of the United States, as is the spread of highly transmissible variants of the virus. Current vaccines and… Read More

Professor David Merryman explains how his team targeted the serotonin 2B receptor in animal models to preserve cardiac function six weeks after a heart attack. Researchers at Vanderbilt University in the US report that they have identified a protein receptor in specialised heart cells that, when removed, preserves cardiac function… Read More