>

Vanderbilt School of Medicine Basic Sciences

Gallbladder Disease Research

It is estimated that there are 20.5 million cases of gallbladder disease in the United States, 14.2 million of whom are in women. Gallbladder cancer is the 22nd most common cancer worldwide. It is the 23rd most common cancer in men and the 20th most common cancer in women.

3-D illustration of Human body Gallbladder anatomy. (Adobe Stock image, by PIC4U)
3-D illustration of Human body Gallbladder anatomy.

Gallbladder Disease Research

Vanderbilt School of Medicine’s Basic Sciences researchers study gallbladder disease by probing the fundamental biology behind gallstone formation and biliary inflammation. Work commonly integrates cell and animal models with human biospecimens. Investigators explore genetic and environmental risk factors, including diet and the gut–liver–biliary axis, and apply modern tools such as multi-omics, advanced microscopy, and organoid-style systems to map disease mechanisms. This mechanistic emphasis supports translation toward better biomarkers, prevention strategies, and targeted therapies for gallstones and related biliary disorders.

School of Medicine Basic Sciences Stomach Disorders Research

Developmental biologists discover how a critical protein shapes gallbladder formation

Giving

Donors play a critical role in supporting our research and graduate and postdoctoral training. Your support will bolster our cutting-edge research-all building towards major advancements in human health and shape the careers of future scientists. Thank you for your support!

Dare To Make A Difference Today!