Schizophrenia
-
Second schizophrenia treatment discovered at Vanderbilt’s Warren Center enters phase I clinical trial
A new potential treatment for schizophrenia discovered through the Warren Center for Neuroscience Drug Discovery at Vanderbilt University has entered phase 1 clinical trials, marking the fifth WCNDD therapeutic to advance into human testing. Read MoreNov. 12, 2025
-
New technique pioneered at Vanderbilt can identify new risk genes for schizophrenia
Bingshan Li and his lab are changing the paradigm of how geneticists can identify risk genes for schizophrenia, enabling new studies into its underlying biology and opening new doors for the development of treatments against it. Read MoreOct. 29, 2025
-
New Warren Center TREK channel compounds reveal power of academic-industry partnerships in drug discovery
What makes these results exceptional isn’t just the compounds themselves, it’s what they represent: the value of translational research grounded in real-world therapeutic goals. The partners chose to release these best-in-class tool compounds to the scientific community to accelerate further discovery. Read MoreJun. 16, 2025
-
Warren Center for Neuroscience Drug Discovery researchers create new compound to potentially treat negative and positive symptoms of schizophrenia
Researchers from the Warren Center for Neuroscience Drug Discovery, in collaboration with Boehringer Ingelheim, developed a compound that can treat both negative and positive symptoms of schizophrenia in rodents. The compound holds promise as an investigational tool and an inspiration for novel schizophrenia therapies. Read MoreJun. 13, 2025
-
New Warren Center TREK channel compounds reveal power of academic-industry partnerships in drug discovery
What makes these results exceptional isn’t just the compounds themselves, it’s what they represent: the value of translational research grounded in real-world therapeutic goals. The partners chose to release these best-in-class tool compounds to the scientific community to accelerate further discovery. Read MoreJun. 5, 2025
-
Warren Center for Neuroscience Drug Discovery researchers create new compound to potentially treat negative and positive symptoms of schizophrenia
Researchers from the Warren Center for Neuroscience Drug Discovery, in collaboration with Boehringer Ingelheim, developed a compound that can treat both negative and positive symptoms of schizophrenia in rodents. The compound holds promise as an investigational tool and an inspiration for novel schizophrenia therapies. Read MoreJan. 16, 2025
-
Warren Center for Neuroscience Drug Discovery inaugural open house offers behind-the-scenes drug discovery research
The Warren Center for Neuroscience Drug Discovery opened its doors to the Nashville community to share firsthand the pioneering work it is conducting on Alzheimer’s disease, Parkinson’s disease, addiction, and more. Read MoreJul. 8, 2024
-
Potential schizophrenia treatment, discovered at Vanderbilt and being developed by Neumora Therapeutics, entering Phase 1 clinical trial
A potential schizophrenia treatment discovered through the Warren Center for Neuroscience Drug Discovery has been cleared by the U.S. Food and Drug Administration for use in phase 1 clinical trials—the third WCNDD therapeutic to reach that benchmark. “Vanderbilt is proud that a discovery by our researchers at the Warren Center… Read MoreDec. 4, 2023
-
A potential new approach for the treatment of schizophrenia
THE IDEA Jeffrey Conn (John Russell/Vanderbilt University) James Maksymetz A new study led by Jeff Conn, Lee E. Limbird Chair in Pharmacology, James Maksymetz, a former graduate student in the Conn laboratory, and other collaborators at the Warren Center for… Read MoreDec. 8, 2021
-
Deciphering the Circuits in Neuroscience Research
Around 500 million people around the world are affected by poor mental health including disorders such as depression, schizophrenia, bipolar disease and dementia with a significant impact on quality of life as well as associated social and economic consequences.1 Boehringer Ingelheim is dedicated to redefining the management of mental health. Read MoreDec. 7, 2021