Cancer

Laboratory of Genome Integrity chief André Nussenzweig will present the Vanderbilt School of Medicine Basic Sciences Apex Lecture on Monday, Dec. 25, 2025. Read More

Vanderbilt researchers led by Ann Richmond have identified a promising drug combination that targets three key pathways in advanced melanoma, potentially restoring the immune response in patients resistant to standard immunotherapy. Although the work is preclinical, the use of drugs already in clinical trials for other conditions could accelerate testing in humans. Read More

Kathleen DelGiorno has received a Research Scholar Award from the American Cancer Society to study pancreatic cancer development. She will focus on the role of two fatty acids that are known to be involved with tumorigenesis. Read More

With a new method, researchers have captured a high-resolution metabolic “map” of how cells orchestrate glucose processing, revealing a hidden world where organelles and molecular complexes collaborate when responding to a rush of nutrients. The results of the pioneering work provide insights into an organizational and molecular framework that can be used to study how metabolic processes are disrupted in diseases and aging. Read More

Vanderbilt Center for Extracellular Vesicle Research members presented their research at the International Society of Extracellular Vesicles conference in Vienna, Austria in late April. Read More

Vanderbilt researchers have developed a nanoparticle complex that can both visualize and attack cancer cells by targeting the tumor microenvironment. Read More

A new study uncovered how tissues detect and respond to damage in basement membranes, and how they recruit a previously unknown set of "matrix mender" cells to repair the tissue. The results of this study have far-reaching implications for numerous diseases, including diabetes, dementia, and cancer. Read More

Meet Naila Tasneem, a research technician in the Department of Cell and Developmental Biology in the Vanderbilt School of Medicine Basic Sciences. Read More

Researchers discovered that the protein tenascin-C is a crucial molecular player in the aggressiveness of anaplastic thyroid cancer. The results could lead to better targeted therapeutics for thyroid cancer. Read More