Cancer
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Anthony Venida deliver Discovery Science Emerging Scholar Lecture on Nov. 19
HHMI Hanna Gray postdoctoral fellow Anthony Venida will present the Discovery Science Emerging Scholar Lecture on Tuesday, Nov. 19. Read MoreNov. 14, 2024
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New structure gives insight into mRNA export and cancers, and how viruses hijack the process to infect their host
A newly determined structure from the lab of Yi Ren reveals information about the mRNA export pathway and suggests that herpes viruses could hijack that interaction to infect their host. The new structures also reveal how certain mutations in the protein complex could play a role in cancers. Read MoreNov. 14, 2024
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Determining the precise timing of cellular growth to understand the origins of cancer
Mirazul Islam, a graduate student in the lab of Professor Ken Lau, has developed a molecular clock that records the timing of cellular events at a single-cell resolution. Read MoreOct. 31, 2024
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Linkous advances lung cancer research with Merck Research Laboratories Scientific Engagement and Emerging Discovery Science program
A research grant to study lung and cerebral organoids will yield insights into the sensitivity of lung and brain tumors to commercially available antibody-drug conjugate payloads. The OVPRI Industry Collaborations group facilitated the collaboration. Read MoreSep. 18, 2024
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Promising drug-like compounds found to have strong action against blood cancers
For researchers, projects can sometimes feel like babies, and there is nothing more satisfying than seeing your baby grow up. For William Tansey, professor of cell and developmental biology, this baby started 10 years ago when he and Stephen Fesik, Orrin H. Ingram II, Professor of Cancer Research and professor… Read MoreSep. 3, 2024
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Vanderbilt basic science alum Q&A: Randy Perera
Randy Perera, Fellow'24, who worked in the biochemistry department and is now a scientist at the pharmaceutical and biotech company MilliporeSigma (Merck KGaA) sat down with us to discuss his experience studying basic science at Vanderbilt and how it played a role in his career. Read MoreJul. 29, 2024
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Vanderbilt-discovered cancer killing compound is now available through Boehringer Ingelheim open science portal opnMe
By targeting a notoriously undruggable protein found in many cancers, the discovery of BI-0474 may pave the way for new cancer treatments. Shared on opnMe.com by Boehringer Ingelheim, this innovative molecule is available for global researchers to explore new research avenues. Read MoreMay. 28, 2024
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Research Snapshot: Understanding protein mutations that affect gene expression
Foundational research from the Hiebert lab reveals genetic targets that can be leveraged to identify therapies that affect lymphoma cell growth. Read MoreMay. 23, 2024
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New cancer target could push new drugs into the clinic
New work by Professor of Cell and Developmental Biology Bill Tansey and colleagues has determined that a new type of inhibitor—a WINi—targets cancer cells in a novel way and suggests exploiting this pathway in future anticancer drug development efforts. Read MoreMay. 14, 2024
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A Nobel-worthy discovery spawns a new field—and new therapies
Cohen was awarded the 1986 Nobel Prize in Physiology or Medicine for his discovery of epidermal growth factor, a protein produced in the body that influences the development of nerve and skin tissues by stimulating cell growth and differentiation. The discovery of EGF launched an entire field of research into growth factor signaling and had major impacts on human health. Read MoreMar. 7, 2024