Cancer

A new study uncovered how tissues detect and respond to damage in basement membranes, and how they recruit a previously unknown set of "matrix mender" cells to repair the tissue. The results of this study have far-reaching implications for numerous diseases, including diabetes, dementia, and cancer. Read More

Meet Naila Tasneem, a research technician in the Department of Cell and Developmental Biology in the Vanderbilt School of Medicine Basic Sciences. Read More

Researchers discovered that the protein tenascin-C is a crucial molecular player in the aggressiveness of anaplastic thyroid cancer. The results could lead to better targeted therapeutics for thyroid cancer. Read More

Triple-negative breast cancer accounts for 10 percent of breast cancer cases in the U.S. annually. As T-cells that normally kill cancer cells often become exhausted and stop, Vanderbilt pharmacologists are seeking chemotherapy or targeted therapy approaches that can enhance the T-cell killing of cancer cells. Read More

Eunyoung Choi and Ken Lau receive funding for novel cancer research, which may ultimately result in cancer detection and treatment options for patients. The fund supports early-stage, high-risk high-reward research projects and honor Cohen’s seminal discoveries, which led to the invention of many anticancer drugs used today. Read More

The Center for Extracellular Vesicle Research, which is made up of over 20 laboratories spanning Vanderbilt University, held its annual retreat in late September. Researchers discussed the types of biomolecular cargoes EVs contain and how EVs holding unique cargoes can be used as diagnostic tools. Read More

HHMI Hanna Gray postdoctoral fellow Anthony Venida will present the Discovery Science Emerging Scholar Lecture on Tuesday, Nov. 19. Read More

A newly determined structure from the lab of Yi Ren reveals information about the mRNA export pathway and suggests that herpes viruses could hijack that interaction to infect their host. The new structures also reveal how certain mutations in the protein complex could play a role in cancers. Read More

Mirazul Islam, a graduate student in the lab of Professor Ken Lau, has developed a molecular clock that records the timing of cellular events at a single-cell resolution. Read More

A research grant to study lung and cerebral organoids will yield insights into the sensitivity of lung and brain tumors to commercially available antibody-drug conjugate payloads. The OVPRI Industry Collaborations group facilitated the collaboration. Read More