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Depression

  • Vanderbilt University

    Getting more bang for your buck

    Ever wonder what about the ROI on biomedical research looks like? At the Vanderbilt University School of Medicine Basic Sciences, scientists are delivering answers—by driving discoveries that are already improving human health and paving the way for tomorrow’s treatments. This 2025–26 roundup highlights some of the year’s most exciting advances, showing the extraordinary value of sustained support for biomedical science. Read More

    Apr. 14, 2026

  • Brain Disorders Research – Original

    Brain Disorders Research – Original

      Link List – Right Hand Column PlaceholderRefresh After Saving to Remove .link-list.jump-links{ padding-left: 0 !important; } CENTERS & INSTITUTES: Vanderbilt Center for Addiction Research (VCAR) Warren Center for Neuroscience Drug Discovery (WCNDD) Vanderbilt Brain Institute The Brain Diseases affecting… Read More

    Jan. 25, 2026

  • Brain Disorders Research

    Brain Disorders Research

    Link List – Right Hand Column PlaceholderRefresh After Saving to Remove .link-list.jump-links{ padding-left: 0 !important; } CENTERS & INSTITUTES: Vanderbilt Center for Addiction Research (VCAR) Warren Center for Neuroscience Drug Discovery (WCNDD) Vanderbilt Brain Institute The Brain Diseases affecting the… Read More

    Jan. 9, 2026

  • Graphic showing a paper cut-out of a person's head that's been crumpled and spread out again, showing creases throughout. The background is made up of rough, concentric layers of black paper with the center torn out. The image makes it feel like the world is closing in on the person.

    New ketamine study promises extended relief for depression

    Major depression is one of the most common mental disorders in the U.S. Approximately 7% (17.3 million) of American adults had at least one major depressive episode in 2017. Roughly 10 percent of the U.S. population is afflicted with major depressive disorder at any… Read More

    Jun. 13, 2025

  • A 3D rendering of several neural synapses.

    New ketamine study promises extended relief for depression

    For the nearly 30 percent of major depressive disorder patients who are resistant to treatment, ketamine provides some amount of normalcy, but it requires frequent treatment and can have side effects. Vanderbilt researchers now show in proof-of-concept experiments that it may be possible to extend ketamine’s antidepressant effect from about a week to up to two months. Read More

    May. 22, 2025

  • Vanderbilt University

    Treatment-resistant depression linked to body mass index: study

    Genetic factors are a small but significant contributor to severe depression that does not respond to standard therapy, according to researchers at Vanderbilt University Medical Center and Massachusetts General Hospital. Read More

    May. 24, 2024

  • Vanderbilt University

    Understanding the molecules and brain circuits recruited by stressful experience

    Stressful experiences can lead to adaptive or detrimental behaviors. Understanding how stress can affect our brains can help understand basic brain function and is also essential to discerning causes and treatments for some diseases. A group of researchers led by Jeffrey Conn, professor of pharmacology at… Read More

    Feb. 18, 2022

  • Vanderbilt University

    Deciphering the Circuits in Neuroscience Research

    Around 500 million people around the world are affected by poor mental health including disorders such as depression, schizophrenia, bipolar disease and dementia with a significant impact on quality of life as well as associated social and economic consequences.1 Boehringer Ingelheim is dedicated to redefining the management of mental health. Read More

    Dec. 7, 2021

  • A teal piece of paper in the shape of a downcast head sits on top of torn black paper. The torn paper is arranged in concentric circles with the head in the center.

    Receptor modulators chart new courses out of depression

    By Amanda N. Johnson “Major depression is one of the most common mental disorders in the U.S. According to the National Institute of Mental Health, approximately 7% (17.3 million) of American adults had at least one major depressive episode in 2017.” (Tadamichi, stock.adobe.com) Existing drug treatments relieve mental illness for… Read More

    Feb. 4, 2020