Jens Meiler
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Unlocking the Secrets of Protein Folding
It’s often the simplest and most informal of invitations that can open a world of endless possibilities and lifelong relationships. That’s how Professor Jens Meiler’s extraordinary scientific journey began in the lab of Nobel Prize winner David Baker. What has he made of the opportunities presented to him that day? Read MoreOct. 18, 2024
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Expert in bio-inspired AI systems visits Vanderbilt to discuss the future potential of neuromorphic supercomputers
At a recent Center for Applied AI in Protein Dynamics seminar, Christian Mayr of Technische Universität Dresden discussed how new hardware technologies will transform AI development and allow machines to mimic the efficiency and processing power of the human brain. Read MoreAug. 26, 2024
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New drug candidates targeting blood clots developed through computer-aided drug design
Using computer-aided drug design, the labs of Heidi Hamm, Jens Meiler, and Craig Lindsley generated a novel series of biologically active compounds that can serve as a basis for anti–blood clot preventative drugs. Read MoreJun. 6, 2024
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School of Medicine Basic Sciences Staff Spotlight: Karen Davis
Karen Davis, the program coordinator for the Center for Structural Biology, enjoys feeling like she is "a part of something bigger” than herself, both in and out of the office. She is a huge soccer fan and coaches two co-ed recreational soccer teams at the Nashville Youth Soccer Association. Read MoreApr. 17, 2024
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The Expert from Nowhere
To understand a protein’s structure is to understand its function, says structural and chemical biologist Jens Meiler, PhD, distinguished research professor of Chemistry. It can take a PhD student up to five sleep-deprived years to determine the structure of a single protein, and of the 20,000 human proteins, only about… Read MoreJan. 26, 2023
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Study reveals need for matching targeted therapies with EGFR subtypes
New research from Vanderbilt investigators suggests that clinicians should take a deeper dive into distinguishing EGFR mutations when prescribing targeted therapies for non-small-cell lung cancers. EGFR exon 19 deletion mutations are the most common EGFR mutations in patients with lung cancer. However, the term “exon 19 deletion” is a catch-all… Read MoreJul. 28, 2022
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Collaborative research yields new protein structure
Structure of a caveolin-1 complex obtained using cryo-electron microscopy. A protomer, or a structural unit, is highlighted in magenta. The image was cropped to focus on panel A of Figure 1 of the paper, modified and published here in accordance to a CC BY-NC 4.0 license. Read MoreMay. 16, 2022
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Eichman, Meiler and five Vanderbilt faculty elected AAAS fellows in 2021
Seven Vanderbilt University and Vanderbilt University Medical Center faculty members have been elected 2021 fellows of the American Association for the Advancement of Science, an honor bestowed upon AAAS members by their peers. Among those elected is Provost and Vice Chancellor for Academic Affairs Cybele Raver,… Read MoreJan. 26, 2022