Liver

Obesity and overnutrition increase the risk of Type 2 diabetes through several mechanisms. One of these is through loss of the insulin-producing beta cells of the pancreatic islet. Wenbiao Chen, PhD, and colleagues previously have shown that overnutrition stressed the endoplasmic reticulum, the part of the beta… Read More

Type 2 diabetes, which affects more than 30 million Americans, increases risk of cardiovascular disease. Nearly 70% of people with Type 2 diabetes die from heart disease or stroke. Maureen Gannon, PhD, and colleagues investigated the role of the inflammatory lipid signaling molecule PGE2 — acting through… Read More

By Heather Caslin Approximately 30 million Americans have type 2 diabetes. The majority are over 45 years old. © Vitalii Vodolazskyi, stock.adobe.com Within the pancreas, β-cells produce insulin that delivers energy to tissues through glucose. People with type 2 diabetes have smaller, less functional β-cells; however, the mechanisms that drive… Read More

by Jill Clendening Vanderbilt University Medical Center researchers say an unexpected finding during the cellular analysis of human pancreatic tissue has revealed new information about a rare type of diabetes and underscores the importance of genetic testing for some individuals diagnosed with type 1 diabetes. The research centers on… Read More