National Institutes Of Health

Phase I clinical trial of drug was successfully completed at the Warren Center for Neuroscience Drug Discovery, with promise to treat Alzheimer’s and other neurodegenerative diseases. The compound, named VU319, is the first Vanderbilt end-to-end drug discovery effort related to memory loss, starting from the earliest basic science research through human clinical trials. Read More

Colorectal cancer is the second leading cause of cancer-related deaths in the U.S. Ken Lau and Jeffrey Spraggins are creating the first spatially mapped atlas characterizing the progression trajectories of early-onset colorectal cancer versus average-onset CRC as they transition from precancerous lesions to malignant cancers. Read More

In 2024 the National Institutes of Health awarded Sando a New Innovator Award, part of their High-Risk, High-Reward Research program. This award, which provides $1,500,000 over five years, supports early-career scientists proposing innovative and impactful research that might not get funded in the traditional peer-review process due to its inherent risk. Read More

Research from Teru Nakagawa, professor of molecular physiology and biophysics, describes intricacies of normal brain function with implications for our understanding of brain injury and recovery: A decrease in pH can modify a neurotransmitter receptor’s structure, thereby modulating its location and kinetics. Read More

The National Institute of Diabetes and Digestive and Kidney Diseases of the National Institutes of Health has renewed a five-year grant through the NIH’s flagship T32 institutional training grant program. T32 grants provide funding to support students and postdoctoral trainees working in focused areas of research that advance the NIH mission. Read More

In a recent episode of Smarter Every Day, YouTube sensation and host Destin Sandlin talks with Vanderbilt Professor Tina Iverson and Senior Research Associate Prashant Singh about bacterial “motors” and how they work in the microorganisms that make us sick. The video racked up more than 1.4 million views in its first day. Read More

Jeffrey Spraggins, a leading scientist in imaging mass spectrometry, has been named director of the Mass Spectrometry Research Center. The MSRC is a highly collaborative research entity incorporating a wide range of technologies and serving hundreds of users, including partnering with pharmaceutical companies on drug development research. Read More

Using computer-aided drug design, the labs of Heidi Hamm, Jens Meiler, and Craig Lindsley generated a novel series of biologically active compounds that can serve as a basis for anti–blood clot preventative drugs. Read More

The Vanderbilt School of Medicine Basic Sciences’ pharmacology department and the Vanderbilt Center for Addiction Research hosted a special event on April 22 focused on the importance of funding for diverse trainees and faculty in academic settings. The speakers discussed the various grants to fund underrepresented trainees and faculty at various stages in their career. Read More

By targeting a notoriously undruggable protein found in many cancers, the discovery of BI-0474 may pave the way for new cancer treatments. Shared on opnMe.com by Boehringer Ingelheim, this innovative molecule is available for global researchers to explore new research avenues. Read More