Pharmacology
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Erin Calipari receives $2M to study how alcohol use disorder develops in the brain
Erin Calipari, associate professor of pharmacology and associate director of the Vanderbilt Center for Addiction Research, has received a grant of nearly $2 million from the National Institute on Alcohol Abuse and Alcoholism to understand what happens in the brain that makes… Read MoreSep. 13, 2023
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Basic Sciences names Hodges, Siciliano as Dean’s Faculty Fellows
By Aaron Conley Emily Hodges, assistant professor of biochemistry, and Cody Siciliano, assistant professor of pharmacology, have been named Dean’s Faculty Fellows of the School of Medicine Basic Sciences. The Dean’s Faculty Fellows program, started in 2020, is designed to recognize the efforts of faculty in the early… Read MoreAug. 18, 2023
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Study identifies key regulator of melanoma development
Vanderbilt investigators have revealed the mechanisms by which the chemokine receptor CXCR2, is associated with melanoma tumor formation and growth — a discovery that supports the continued development of drugs that inhibit the receptor’s activity. Ann Richmond, PhD, Ingram Professor of Cancer Biology and professor of Pharmacology, is internationally known… Read MoreJul. 6, 2023
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Study identifies key regulator of melanoma development
Vanderbilt investigators have revealed the mechanisms by which the chemokine receptor CXCR2, is associated with melanoma tumor formation and growth — a discovery that supports the continued development of drugs that inhibit the receptor’s activity. Ann Richmond, PhD, Ingram Professor of Cancer Biology and professor of Pharmacology, is internationally known… Read MoreJun. 15, 2023
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Targeting calcium handling in A-fib
Atrial fibrillation (A-fib) — the most common cardiac arrhythmia (irregular heartbeat) — is associated with increased risk of stroke, heart failure, dementia and death. Antiarrhythmic drug therapy to prevent A-fib has remained elusive. The strongest genetic risk factors for A-fib in humans are variants in a chromosomal region including the gene… Read MoreJun. 15, 2023
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Vanderbilt mourns loss of renowned clinical pharmacologist Jackson Roberts II, MD
Jackson Roberts II, MD, an internationally known clinical pharmacologist in the Vanderbilt University School of Medicine who helped define the role of lipid peroxidation and oxidative stress in human disease, died May 31 in Nashville. He was 79. Dr. Roberts, professor of Pharmacology and Medicine, emeritus, was perhaps best known… Read MoreJun. 6, 2023
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Lindsley named 2022 fellow of American Society for Pharmacology and Experimental Therapeutics
Craig W. Lindsley, University Distinguished Professor of Pharmacology, Biochemistry and Chemistry, who holds the William K. Warren, Jr. Chair in Medicine, was recently announced as a 2022 fellow of the American Society for Pharmacology and Experimental Therapeutics for his demonstrated excellence and… Read MoreNov. 30, 2022
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Basic Sciences mourns the loss of Reynolds
By Leah Mann Graduate student Sarah Kurley with thesis advisor Al Reynolds. (Photo by Mary Donaldson) Albert “Al” Reynolds, celebrated and respected professor of pharmacology, emeritus, passed away earlier in November. He had retired in August after 26 years at Vanderbilt University. In the nearly three decades of Reynolds’ affiliation… Read MoreNov. 15, 2022
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Nanoparticles boost anti-cancer immunity
The growth of epithelial ovarian cancer, one of the most lethal malignancies, is associated with the presence of tumor-associated macrophages (TAMs), white blood cells that can block the anti-cancer activity of the immune system and immunotherapy. Fortunately, TAMs can be “repolarized,” converted from immunosuppressive tumor-promoters to inflammatory tumor-fighters. Now,… Read MoreAug. 18, 2022
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Mass spectrometry analysis reveals massive insight into neuronal signaling
Heidi Hamm, Yun Young Yim By Emily Overway Researchers in the lab of Heidi Hamm, a professor of pharmacology who also holds the Aileen M. Lange and Annie Mary Lyle Chair in Cardiovascular Research, recently published a paper exploring the G protein subunits that interact with the SNARE complex. The… Read MoreMar. 3, 2022