School Of Medicine Basic Sciences
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Vanderbilt and Northwestern labs discover new mechanisms that cause irregular heartbeat
Vanderbilt and Northwestern University researchers characterized a group of KCNQ1 variants probe their role in a common heart disorder called LQTS. They found that there are five classes of mutations that act through independent mechanisms, suggesting that a more tailored/personalized treatment approach could be beneficial for LQTS patients. Read MoreFeb. 18, 2025
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Does your liver know what time it is?
Physician-scientist Mitch Lazar delivered a School of Medicine Basic Sciences Apex Lecture on Feb. 11 about nuclear receptors and the circadian regulation of metabolism. Read MoreFeb. 18, 2025
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Greater than the sum of its parts: the role of VARP-SNX27 binding in endosomal “supercomplex” formation
The lab of Lauren Jackson provides the first evidence of an endosomal “supercomplex” and reveals a vital role for VARP in mediating coat assembly in a recent paper published in Science Advances. Read MoreFeb. 17, 2025
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Molecular biologist David Bartel delivers Apex Lecture on target-directed microRNA degradation
Renowned Massachusetts Institute of Technology molecular biologist David Bartel delivered a School of Medicine Basic Sciences Apex Lecture on Jan. 15 about the regulation of mRNA translation and decay. Read MoreFeb. 6, 2025
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How do you maintain a cellular structure without a membrane? Researchers find that synapses can use liquids to create functional separations
Researchers from the School of Medicine Basic Sciences found that, although synapses are not bound by a membrane, they are still able to maintain a nanostructure necessary for evoked neurotransmission with the help of a physicochemical phenomenon called liquid-liquid phase separation. Read MoreFeb. 6, 2025
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School of Medicine Basic Sciences Staff Spotlight: Elana Milano
Meet Elana Milano, program manager for research for the Department of Molecular Physiology and Biophysics in the School of Medicine Basic Sciences. Read MoreFeb. 4, 2025
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Choosing and managing the trainees and staff in your new lab
People are complicated and so it should be no surprise that among the most difficult tasks that you’ll face as a research group leader in science is recruiting and successfully managing talented and collegial students, postdocs, and staff. This may be especially true for assistant professors and their peers in industry or at research institutes. Read MoreFeb. 4, 2025
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Developmental biologists discover how a critical protein shapes gallbladder formation
Researchers from the School of Medicine Basic Sciences have discovered that the concentration of a critical protein influences the formation of the gallbladder and the bile duct system. Read MoreJan. 30, 2025
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Physician-scientist Mitch Lazar to deliver Apex Lecture on Feb. 11
Whitehead Institute Professor of Biology David Bartel will present a Vanderbilt School of Medicine Basic Sciences Apex Lecture on Feb. 11, 2025. Read MoreJan. 22, 2025
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Vanderbilt basic science alum Q&A: Ashley Brady
Ashley Brady, PhD’03, assistant dean of biomedical career engagement and strategic partnerships in the BRET Office of Career Development ASPIRE Program and associate professor of medical education and administration, sat down with us to discuss her experience studying basic science at Vanderbilt and how it played a role in her career. Read MoreJan. 21, 2025