Skin Cancer
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Targeting immune suppression to overcome melanoma resistance
Ann Richmond outlines a promising therapeutic strategy that may re-sensitize treatment-resistant tumors to immunotherapy. The research introduces a three-drug combination that enhances immune activity and suppresses tumor-promoting immune cells. Read MoreFeb. 16, 2026
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Promising new drug combination may help melanoma patients resistant to treatment respond once again to the body’s immune defenses
Vanderbilt researchers led by Ann Richmond have identified a promising drug combination that targets three key pathways in advanced melanoma, potentially restoring the immune response in patients resistant to standard immunotherapy. Although the work is preclinical, the use of drugs already in clinical trials for other conditions could accelerate testing in humans. Read MoreOct. 15, 2025
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Vanderbilt team discovers potential explanation for treatment resistance in skin cancer
Many melanoma patients are treated with drugs called BRAF or MEK inhibitors that specifically target the mutant proteins created in cancerous tumors. These inhibitors can block the tumors’ ability to grow and spread. According to Ann Richmond, Ingram Professor of Cancer Research and professor of pharmacology… Read MoreFeb. 28, 2022