Structural Biology

A newly determined structure from the lab of Yi Ren reveals information about the mRNA export pathway and suggests that herpes viruses could hijack that interaction to infect their host. The new structures also reveal how certain mutations in the protein complex could play a role in cancers. Read More

Nobel Prize winner Venki Ramakrishnan delivered a captivating talk as part of the School of Medicine Basic Sciences Apex Lecture Series. His presentation was based on his best-selling book, Why We Die, which explores the biological mechanisms behind aging and death and humanity's efforts to prolong life. Read More

As a fifth-year graduate student in the Biochemistry Graduate Program, Jenny focuses on dissecting the allostery involved in heme biosynthesis initiation using an integrated structural biology approach in the lab of Professor Breann Brown. Her work has led to collaborations with other Vanderbilt labs, including the labs of Jens Meiler, John Yang and Jason MacGurn. Read More

In a recent episode of Smarter Every Day, YouTube sensation and host Destin Sandlin talks with Vanderbilt Professor Tina Iverson and Senior Research Associate Prashant Singh about bacterial “motors” and how they work in the microorganisms that make us sick. The video racked up more than 1.4 million views in its first day. Read More

The 2024 Center for Structural Biology Symposium, which took place on March 28, celebrated its decades of success, research undertakings, and goal of strengthening the structural biology community at Vanderbilt. Read More

Structure of a caveolin-1 complex obtained using cryo-electron microscopy. A protomer, or a structural unit, is highlighted in magenta. The image was cropped to focus on panel A of Figure 1 of the paper, modified and published here in accordance to a CC BY-NC 4.0 license. Read More