Warren Center For Neuroscience Drug Discovery

Niswender’s project seeks to understand why levels of mGlu7 are reduced in Rett syndrome and to test a new therapeutic approach using DNA molecules to restore those levels. This work could pave the way for new drug therapies to address symptoms of Rett syndrome and related disorders, while also advancing advocacy and visibility for these conditions in the scientific community. Read More

A new potential treatment for schizophrenia discovered through the Warren Center for Neuroscience Drug Discovery at Vanderbilt University has entered phase 1 clinical trials, marking the fifth WCNDD therapeutic to advance into human testing. Read More

Meet Hannah Schaeffer, administrative manager for the Warren Center for Neuroscience Drug Discovery. Read More

Meet Sheila Elder, an administrative officer in the Vanderbilt University School of Medicine Basic Sciences who provides financial and administrative leadership for the Warren Center for Neuroscience Drug Discovery. Read More

What makes these results exceptional isn’t just the compounds themselves, it’s what they represent: the value of translational research grounded in real-world therapeutic goals. The partners chose to release these best-in-class tool compounds to the scientific community to accelerate further discovery. Read More

Researchers from the Warren Center for Neuroscience Drug Discovery, in collaboration with Boehringer Ingelheim, developed a compound that can treat both negative and positive symptoms of schizophrenia in rodents. The compound holds promise as an investigational tool and an inspiration for novel schizophrenia therapies. Read More

What makes these results exceptional isn’t just the compounds themselves, it’s what they represent: the value of translational research grounded in real-world therapeutic goals. The partners chose to release these best-in-class tool compounds to the scientific community to accelerate further discovery. Read More

In this episode of Quantum Potential, Craig Lindsley, William K. Warren, Jr. Professor of Medicine, University Distinguished Professor of Biochemistry, Chemistry and Pharmacology and executive director of the Warren Center for Neuroscience Drug Discovery, joins Provost C. Cybele Raver to discuss transformative research exploring how subtle tweaks to brain chemistry could change the way we treat neurodegenerative diseases and chronic pain. Lindsley shares how academic-industry collaborations drive innovation in drug discovery and highlights how Vanderbilt’s scientific workflow is enabling the broader research community to build on its breakthroughs. Read More

Great Britain’s Wellcome Trust has recognized Vanderbilt’s Carrie K. Jones and the University of Glasgow’s Andrew Tobin with their prestigious Discovery Award. The pair will study how blocking the M5 muscarinic receptor in the brain counteracts opioids’ addictive properties, which could lead to new treatments for preventing or addressing opioid addiction. Read More

Ashley Brady, PhD’03, assistant dean of biomedical career engagement and strategic partnerships in the BRET Office of Career Development ASPIRE Program and associate professor of medical education and administration, sat down with us to discuss her experience studying basic science at Vanderbilt and how it played a role in her career. Read More