Findings offer new insight on how cell division proteins work
Kathleen Gould, Melanie Ohi, and colleagues have found that certain proteins involved in cell division don’t function as previously thought. Instead of bending membranes into tubes, these “F-BAR” proteins — named for a domain they share — appear to form patches on the membrane where the cell’s internal actin cytoskeleton and other proteins can bind and exert force on the membrane.