Matrigel Mattress: A Method for the Generation of Single Contracting Human-Induced Pluripotent Stem Cell-Derived Cardiomyocytes.
AUTHORS
Feaster
TK ,
Cadar
AG ,
Wang
L ,
Williams
CH ,
Chun
YW ,
Hempel
JE ,
Bloodworth
N ,
Merryman
WD ,
Lim
CC ,
Wu
JC ,
Knollmann
BC ,
Hong
CC ,
. Circulation research. 2015 12 4; 117(12). 995-1000
- PMID: 26429802 [PubMed].
- PMCID: PMC4670592.
- NIHMSID: NIHMS728051
ABSTRACT
The lack of measurable single-cell contractility of human-induced pluripotent stem cell-derived cardiac myocytes (hiPSC-CMs) currently limits the utility of hiPSC-CMs for evaluating contractile performance for both basic research and drug discovery.
The lack of measurable single-cell contractility of human-induced pluripotent stem cell-derived cardiac myocytes (hiPSC-CMs) currently limits the utility of hiPSC-CMs for evaluating contractile performance for both basic research and drug discovery.
Tags: 2015