Molecular Physiology & Biophysics

Author

Vanderbilt Institute of Obesity and Metabolism

Jul. 22, 2014—The Vanderbilt Institute for Obesity and Metabolism was created in 2008, under the direction of Roger Cone, PhD., Professor and Chair of Molecular Physiology and Biophysics. The VIOM provides opportunities for synergy and collaboration among basic scientists, clinicians, and public health professionals at Vanderbilt and its community partners. Another key role of the Obesity Program is to...

MPB wins four of the 2018 faculty awards from the School of Medicine. L-R. Roger Colbran, Charles R. Park Award. Dave Wasserman, John H. Exton Award. Hassane Mchaourab, Stanley Cohen Award. Owen McGuinness, Jacek Hawiger Award.

Sep. 13, 2008—

GLP-1 neurons in the brainstem (located in the nucleus of the solitary tract) relay information from the stomach to the hypothalamus and function to control feeding. Here GLP-1 neurons have been labeled with a genetically targeted fluorescent marker that allows visualization of GLP-1 circuits in order to study how the hormone leptin directs formation of these circuits during development. Image credit: Drs. Jessica Biddinger and Richard Simerly.

Sep. 13, 2007—

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Sep. 13, 2006—

Kim Montaniel in David Harrison’s laboratory studies fibrosis and inflammation in hypertension. Here bone marrow derived cells (bright green) are seen at sites of fibrosis (bright red) in a mouse model of hypertension.

Sep. 13, 2005—

Inflammation of adipose tissue (fat) is thought to contribute to disruption of the endocrine functions of adipose tissue observed in obesity.

Sep. 13, 2004—

The Islet of Langerhans is a small endocrine organ that produces several metabolically critical hormones including insulin. Insulin (stained in green) is produced in β cells which are marked here with a red fluorescent protein produced only in β cells. Lisette Maddison in Wenbiao Chen’s lab uses the zebrafish as a genetic model to study how β cell number is regulated by nutrition.

Sep. 13, 2003—

Our students enjoyed lunch with the 2012 winner of the Nobel Prize in Chemistry, Brian Kobilka M.D., currently a Professor of Molecular and Cellular Physiology at Stanford, and presenter of the 10th Earl W. Sutherland Lecture in MPB on April 5, 2018

Sep. 13, 2002—

Filled dendrites (green) from neurons expressing wild type CaMKII or the ASD-linked E183V mutant (red; left, right, respectively), with a computerized reconstruction highlighting the dendritic spines (Jay Stephenson, Postdoc, Colbran Lab)

Sep. 13, 2001—

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Sep. 13, 2000—