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Michael Joshua Litt, BA

MD PhD Student, Cone laboratory, Molecular Physiology & Biophysics

In the Cone lab, I study the pathophysiology associated with deletion of the MC4R, the most common monogenetic obesity syndrome in man (1/5000 allele frequency). Using the mouse as a model organism, I am characterizing the cardiovascular, metabolic and energetic consequences that result from MC4R deletion. Observations from my research have furthered the need to identify and monitor patients with this distinct obesity syndrome.


More broadly, my research interests include: energy metabolism, mitochondrial physiology, cardiovascular pathophysiology, pharmicogenomics, and gene environment interactions.