Skip to main content

Molecular Physiology & Biophysics

Longitudinally collected CTCs and CTC-clusters and clinical outcomes of metastatic breast cancer.

AUTHORS

Wang C , Mu Z , Chervoneva I , Austin L , Ye Z , Rossi G , Palazzo JP , Sun C , Abu-Khalaf M , Myers RE , Zhu Z , Ba Y , Li B , Hou L , Cristofanilli M , Yang H , . Breast cancer research and treatment. 2017 1 ; 161(1). 83-94

ABSTRACT

Circulating tumor cell (CTC) is a well-established prognosis predictor for metastatic breast cancer (MBC), and CTC-cluster exhibits significantly higher metastasis-promoting capability than individual CTCs. Because measurement of CTCs and CTC-clusters at a single time point may underestimate their prognostic values, we aimed to analyze longitudinally collected CTCs and CTC-clusters in MBC prognostication.

Circulating tumor cell (CTC) is a well-established prognosis predictor for metastatic breast cancer (MBC), and CTC-cluster exhibits significantly higher metastasis-promoting capability than individual CTCs. Because measurement of CTCs and CTC-clusters at a single time point may underestimate their prognostic values, we aimed to analyze longitudinally collected CTCs and CTC-clusters in MBC prognostication.

Tags: