Mitochondrial Haplogroups Modify the Effect of Diabetes Duration and HbA1c on Proliferative Diabetic Retinopathy Risk in Patients With Type 2 Diabetes.
AUTHORS
Mitchell
SL ,
Neininger
AC ,
Bruce
CN ,
Chocron
IM ,
Bregman
JA ,
Estopinal
CB ,
Muhammad
A ,
Umfress
AC ,
Jarrell
KL ,
Warden
C ,
Harlow
PA ,
Wellons
M ,
Samuels
DC ,
Brantley
MA ,
. Investigative ophthalmology & visual science. 2017 12 1; 58(14). 6481-6488
- PMID: 29288266 [PubMed].
- PMCID: PMC5749245.
ABSTRACT
We previously demonstrated an association between European mitochondrial haplogroups and proliferative diabetic retinopathy (PDR). The purpose of this study was to determine how the relationship between these haplogroups and both diabetes duration and hyperglycemia, two major risk factors for diabetic retinopathy (DR), affect PDR prevalence.
We previously demonstrated an association between European mitochondrial haplogroups and proliferative diabetic retinopathy (PDR). The purpose of this study was to determine how the relationship between these haplogroups and both diabetes duration and hyperglycemia, two major risk factors for diabetic retinopathy (DR), affect PDR prevalence.
Tags: 2017