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Renal Denervation Prevents Immune Cell Activation and Renal Inflammation in Angiotensin II-Induced Hypertension.


AUTHORS

Xiao L , Kirabo A , Wu J , Saleh MA , Zhu L , Wang F , Takahashi T , Loperena R , Foss JD , Mernaugh RL , Chen W , Roberts J , Osborn JW , Itani HA , Harrison DG , . Circulation research. 2015 8 28; 117(6). 547-57

ABSTRACT

Inflammation and adaptive immunity play a crucial role in the development of hypertension. Angiotensin II and probably other hypertensive stimuli activate the central nervous system and promote T-cell activation and end-organ damage in peripheral tissues.


Inflammation and adaptive immunity play a crucial role in the development of hypertension. Angiotensin II and probably other hypertensive stimuli activate the central nervous system and promote T-cell activation and end-organ damage in peripheral tissues.


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