University of Arkansas
Manus Donahue lab
My project focuses on developing novel magnetic resonance imaging acquisition and post-processing methods to characterize the brain’s glymphatic system. I have developed a machine learning post-processing algorithm to segment the choroid plexus and quantify its perfusion acquired from arterial spin labeled MRI. The goal is to use this data and develop a cervical lymphangiography method to gain more insight into how glymphatic waste clearance works in humans and how it can become impaired with aging and neurodegenerative disease, such as Parkinson’s disease and Alzheimer’s disease.