Stephen Doster
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Study explores new urinary tract infection treatment
Neil Osheroff, PhD, professor of Biochemistry and Medicine, is part of an international research collaboration resulting in what is on track to be the first new antibiotic treatment for uncomplicated urinary tract infections (uUTI) in more than 20 years. “We now have a direct path connecting the work conducted in our… Read MoreFeb. 2, 2023
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Nutrient absorption disease model
Mutations in the gene MYO5B cause microvillus inclusion disease (MVID), which prevents nutrient absorption in the intestines and is characterized by severe watery diarrhea that typically starts in the first hours after birth. People with MVID usually require lifelong intravenous feedings (parenteral nutrition) or small bowel transplantation. … Read MoreFeb. 2, 2023
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Jenkins named Assistant Dean for DEI
Dear Basic Sciences Community, We are pleased to announce that Felysha Jenkins, Ph.D., has accepted the position of Assistant Dean for Diversity, Equity, and Inclusion in Basic Sciences. Jenkins was hired as the Basic Sciences diversity, equity, and inclusion program manager starting in the late summer of 2021. In her… Read MoreFeb. 1, 2023
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Congressional rules regarding gifts to covered federal elected officials
Colleagues, As in years past, the Office of Federal Relations (www.vanderbilt.edu/federalrelations) is providing a reminder on the Congressional Rules regarding gifts to covered federal elected officials (including athletic tickets, travel to campus, and meals) and our obligations with respect to reporting lobbying activities made on behalf of… Read MoreJan. 27, 2023
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Study identifies human proteins with segments devoid of genetic variation
By Leah Mann Charles Sanders, Ph.D. The lab of Charles Sanders, professor of biochemistry and the Aileen M. Lange and Annie Mary Lyle Chair for Cardiovascular Research, published a study in Protein Science identifying all human proteins that have at least one segment that does not have… Read MoreJan. 27, 2023
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The Expert from Nowhere
To understand a protein’s structure is to understand its function, says structural and chemical biologist Jens Meiler, PhD, distinguished research professor of Chemistry. It can take a PhD student up to five sleep-deprived years to determine the structure of a single protein, and of the 20,000 human proteins, only about… Read MoreJan. 26, 2023
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CRISPR screen identifies role for a specific protein in insulin secretion
By Leah Mann Wenbiao Chen, Ph.D. The labs of Wenbiao Chen, associate professor of molecular physiology and biophysics, and Irina Kaverina, professor of cell and development biology, recently published a study in Molecular Metabolism focused on detecting genes that regulate insulin secretion. The authors demonstrated a new… Read MoreJan. 25, 2023
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Estrada to lead VUSM health equity education
Lourdes Estrada, PhD, associate professor of Biochemistry, has been named assistant dean for Health Equity Education, Vanderbilt University School of Medicine, effective Feb. 1. In this role, she will work to develop and expand initiatives that integrate core principles of health equity into VUSM’s health sciences educational programs, with an… Read MoreJan. 19, 2023
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Study identifies potential new approach for treating lupus
Targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus (SLE) — the most common form of the chronic autoimmune disease lupus. A multidisciplinary team of investigators at Vanderbilt University Medical Center has discovered that blocking an iron uptake receptor reduces disease pathology… Read MoreJan. 19, 2023
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New screening method could pave the way for future cancer drug discoveries
The laboratories of Brian Bachmann, professor of chemistry, biochemistry and pharmacology, and Jonathan Irish, associate professor of cell and developmental biology and pathology, microbiology and immunology, have developed a method to discover new small molecules that may kill cancer cells by working through the body’s immune system. The method is… Read MoreJan. 18, 2023