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NIH grant bolsters research on heart disease, cholesterol
Jan. 22, 2021—Jan. 21, 2021, 10:39 AM by Bill Snyder Thanks to major funding from the National Institutes of Health (NIH), researchers at Vanderbilt University Medical Center have made major inroads in understanding how high-density lipoprotein (HDL), commonly known as good cholesterol, in some cases may actually contribute to the development of atherosclerosis. But there is...
WIN for blocking cancer growth
Jan. 22, 2021—Jan. 21, 2021, 10:00 AM by Sarah Glass WDR5 is a protein that is overexpressed in a variety of cancers. Inhibiting WDR5 by targeting the WDR5-interaction (WIN) site can inhibit the growth of cancer cells in vitro, but this mechanism of action has not been fully elucidated. Publishing in Cell Reports, William Tansey, PhD, Alissa Guarnaccia and...
Early research shows promise for therapeutics that delay Type 2 Diabetes
Jan. 13, 2021—by Marissa Shapiro Jan. 12, 2021, 9:00 AM Vanderbilt researchers have discovered a unique pathway that initiates islet β cell inflammation—a hallmark of type 2 diabetes—putting them a step closer to developing targeted therapeutics for the disease that affects one in 10 Americans. Wenbiao Chen (Vanderbilt University) The article, “RIPK3-mediated inflammation is a conserved β-cell...
Borden Lacy named director of Vanderbilt’s Center for Structural Biology
Jan. 11, 2021—by Marissa Shapiro Jan. 11, 2021, 9:00 AM Borden Lacy (Vanderbilt University) Borden Lacy, Edward and Nancy Fody Chair in Pathology and professor of biochemistry and pathology, microbiology and immunology, has been named director of the Vanderbilt Center for Structural Biology. She is taking the reins from Walter Chazin, Chancellor’s Chair in Medicine and professor...
Siciliano named to 2021 ‘Forbes’ 30 under 30
Jan. 8, 2021—by Marissa Shapiro Jan. 8, 2021, 9:06 AM Vanderbilt alumnus Graham Gaylor and Assistant Professor of Pharmacology Cody Siciliano have been selected for the 2021 Forbes “30 Under 30.” The 10th annual list recognizes 600 entrepreneurs, scientists, activists and entertainers changing the world. Graham Gaylor Gaylor, BS’14, is the cofounder of VRChat, a social network...
Genome editing technique “rescues” mice from accelerated aging disorder: study
Jan. 7, 2021—Jan. 6, 2021, 10:31 AM by Bill Snyder Researchers from the Broad Institute of Harvard and MIT, the National Institutes of Health (NIH) and Vanderbilt University Medical Center for the first time have used a novel genome-editing technique to “rescue” mice from progeria, a rare genetic disease that causes accelerated aging. Their findings, reported this...
Vanderbilt researchers take leadership role in COVID-19 vaccine development
Dec. 18, 2020—by Marissa Shapiro Dec. 18, 2020, 11:55 AM Work on COVID-19 theraputics at Vanderbilt University Medical Center (VUMC) As the United States and the rest of the world witness the rollout of new vaccines targeting COVID-19—as well as better treatment options to fight the virus among infected patients—Vanderbilt University and Vanderbilt University Medical Center have...
Study reveals new strategy for reducing tumor growth, metastasis
Dec. 17, 2020—Dec. 17, 2020, 10:05 AM Ann Richmond, MD, Chi Yan, PhD, Jinming Yang, PhD, and colleagues are studying ways to boost antitumor immunity and reduce tumor growth in breast cancer and melanoma. (photo by Donn Jones) by Leigh MacMillan A team of Vanderbilt investigators has discovered that blocking a certain signaling pathway boosts antitumor immunity...
ANCORA INNOVATIONS – Vanderbilt University | Deerfield
Dec. 17, 2020—REQUEST FOR APPLICATIONS Rare Genetic Diseases Opening January 2021 Rolling Submission-Review Ancora Innovations is a collaboration between Vanderbilt University and Deerfield Management, focused on the union of Vanderbilt’s innovative life science discovery efforts and Deerfield’s commitment to accelerating state-of-the-art drug development. Deerfield will fund Ancora Innovation with up to $65 million to pursue novel therapeutics...
Medium spiny neurons and “sticking” to bad habits
Dec. 15, 2020—By Alexandra Fuller By the time March rolls around, New Year’s resolutions to ditch the expensive lattes and spend less time (and money) shopping online are often far behind us. Activity within the nucleus accumbens, a region of the brain implicated in motivation and addiction, may be at play. Recent work from the labs of...