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Study finds that regulatory protein prevents signaling that triggers cell death
May. 6, 2021—May. 6, 2021, 9:37 AM The team studying the regulation of innate immune response includes (front row, from left) Yang Zhao, PhD, Antiana Richardson, (back row, from left) William Dunker, Xiang Ye, PhD, and John Karijolich, PhD. (photo by Susan Urmy) by Leigh MacMillan A protein implicated in neurodegenerative diseases including amyotrophic lateral sclerosis (ALS)...
A compound to counteract aging?
Apr. 29, 2021—Apr. 29, 2021, 9:53 AM by Leigh MacMillan Aging is a primary risk factor for many chronic diseases. Strategies to slow the aging process and improve health have focused on limiting nutrients, but fasting is difficult. Jason MacGurn, PhD, and colleagues including Robert Dickson, PhD, at the University of Kentucky, have explored a pharmacological approach to increase longevity. Dickson’s...
‘GQ’ magazine editor discusses COVID-19’s impact on addiction and art at Vanderbilt Center for Addiction Research event
Apr. 29, 2021—by Vanderbilt News and Communications Apr. 28, 2021, 12:38 PM by Aaron Conley Drawing on personal experiences, Will Welch, the global editorial director of GQ, discussed COVID-19’s impact on addiction, sobriety and art with Danny Winder, director of the Vanderbilt Center for Addiction Research, and Erin Calipari, assistant professor of pharmacology, during an April 21...
Senior Associate Dean of Basic Sciences Roger Chalkley to Retire
Apr. 23, 2021—Lorena Infante Lara Roger Chalkley, professor of molecular physiology and biophysics and senior associate dean for biomedical research education and training, will be retiring this summer. Chalkley, who has been at Vanderbilt since 1986, is also a co-PI of the Initiative for Maximizing Student Diversity alongside his wife Linda Sealy. Sealy, associate professor emerita of molecular...
3 QUESTIONS ON… How Tumor Cells Grow With Maria Fomicheva of Vanderbilt University
Apr. 22, 2021—Maria Fomicheva (Kaverina lab) is featured in the April 20, 2021 issue of Oncology Times. CRISPR (which stands for “clustered regularly interspaced short palindromic repeats”) is a genome screening tool that allows researchers to edit or delete individual genes—as well as identify the specific genes in the body responsible for certain traits. Now researchers have...
Steve Townsend wins David Y. Gin Young Investigator Award
Apr. 16, 2021—by Marissa Shapiro Apr. 16, 2021, 9:00 AM By Miquéla Thornton Steven Townsend (Vanderbilt University) Assistant Professor of Chemistry Steven D. Townsend has been awarded the 2021 David Y. Gin Young Investigator Award by the American Chemical Society. The award is one that “encourages outstanding contributions to research in carbohydrate chemistry by scientists in the...
New insights into kidney development
Apr. 15, 2021—Apr. 15, 2021, 9:30 AM by Bill Snyder Integrins serve as adhesion receptors for proteins in the extracellular matrix and transduce biochemical signals into the cell. They regulate cell functions including migration, proliferation and apoptosis (programmed cell death). The ILK-PINCH-parvin protein complex (IPP) functions as an intracellular signaling platform for integrins and regulates integrin-mediated signaling pathways. ...
Arrhythmia culprit: supertrafficking ion channel
Apr. 15, 2021—Apr. 15, 2021, 9:00 AM by Leigh MacMillan The potassium channel KCNQ1 plays a critical role in the cardiac action potential — the electrical activity underlying heart muscle contraction. Inherited mutations resulting in loss of channel function or gain of function (GOF) cause heart rhythm abnormalities. Charles Sanders, PhD, and colleagues surveyed known disease-linked GOF mutations in KCNQ1 and...
Vanderbilt research: Better understanding of fundamental cell behavior can improve drug development
Apr. 15, 2021—by Marissa Shapiro Apr. 13, 2021, 9:00 AM Pioneering research from Vanderbilt scientists shows that cells respond differently to acute stress than to gradual stress. The findings establish an entirely new way to look at cell-to-cell communication, or signaling, and may fundamentally change how biomedical researchers study cells. Alexander Thiemicke Gregor Neuert Research led by...
‘GQ’ magazine’s global editorial director to discuss addiction and art at Vanderbilt Center for Addiction Research event April 21
Apr. 15, 2021—by Marissa Shapiro Apr. 13, 2021, 1:28 PM In recognition of Alcohol Awareness Month, the School of Medicine Basic Sciences will host a conversation between Will Welch, global editorial director of GQ magazine, and the Vanderbilt Center for Addiction Research on Wednesday, April 21, from 11 a.m. to noon CT. Registration is required. The virtual...