Stephen Doster

  • Vanderbilt University

    Molecular ‘switch’ may illuminate stomach disorders

    An international team that included researchers from Vanderbilt University Medical Center has discovered a molecular switch that induces rapid proliferation of zymogen granule-secreting chief cells in the stomach to regenerate damaged tissue. The finding, which was reported earlier this month in the journal Cell Stem Cell, may be crucial… Read More

    May. 19, 2022

  • Vanderbilt University

    Study sheds light on the dark side of obesity

    Obesity is an inflammatory condition that can damage tissues throughout the body, resulting in increased risk for cardiovascular disease, insulin resistance, type 2 diabetes and possibly kidney disease. The agents of inflammation are immune cells called macrophages, which accumulate in fatty tissue, and which produce inflammatory chemicals called cytokines. But… Read More

    May. 17, 2022

  • Vanderbilt University

    Collaborative research yields new protein structure

    Structure of a caveolin-1 complex obtained using cryo-electron microscopy. A protomer, or a structural unit, is highlighted in magenta. The image was cropped to focus on panel A of Figure 1 of the paper, modified and published here in accordance to a CC BY-NC 4.0 license. Read More

    May. 16, 2022

  • Vanderbilt University

    Vanderbilt University honors emeritus and emerita faculty

    Vanderbilt University has honored 35 retiring faculty members for their years of service by bestowing upon them the title of emerita or emeritus faculty. They were recognized during Vanderbilt’s Commencement ceremony on May 13. A faculty member who has served the university with distinction over a period of years and… Read More

    May. 13, 2022

  • Vanderbilt University

    Resistance to COVID-19 drug detected in lab study

    The virus that causes COVID-19 can develop partial resistance to the antiviral drug remdesivir during infection of cultured cells in the laboratory by more than one mechanism. The results of the laboratory study led by researchers at Vanderbilt University Medical Center and published April 28 in the journal Science… Read More

    May. 12, 2022

  • Vanderbilt University

    Resistance to COVID-19 drug detected in lab study

    The virus that causes COVID-19 can develop partial resistance to the antiviral drug remdesivir during infection of cultured cells in the laboratory by more than one mechanism. The results of the laboratory study led by researchers at Vanderbilt University Medical Center and published April 28 in the journal Science… Read More

    May. 12, 2022

  • Six biomedical Ph.D. students awarded prestigious NSF Graduate Research Fellowships

    Six biomedical Ph.D. students awarded prestigious NSF Graduate Research Fellowships

    From left to right, top to bottom: Minna Apostolova, Blake Baleami, Andreanna Burman, Drew Dixson, Kevin McCarty, Teresa Piedad Torres, Jose Zepeda, Kaeli Bryant, Julissa Burgos, Heather Hartmann, Reese Martin, Zach Sanchez. By Emily Overway The National Science Foundation Graduate Research Fellowship Program… Read More

    May. 10, 2022

  • Vanderbilt University

    Cryo-EM reveals the molecular mechanism of IP3 receptor channel opening

    Research led by co-first authors Emily Schmitz, a graduate student in the Chemical and Physical Biology program, and Hirohide Takahashi, a research instructor in molecular physiology and biophysics, identified the structure of the human type-3 inositol 1,4,5-triphosphate, or IP3, receptor in several conformations using cryo-electron microscopy. Schmitz and Takahasi, who… Read More

    May. 9, 2022

  • Vanderbilt University

    Researchers investigate self-regulation of an enzyme with critical cellular functions

    he lab of Kathy Gould, Louise B. McGavock Professor and professor of cell and developmental biology, used a multi-disciplinary approach that included structural biology, biochemistry, and molecular biology to investigate the regulation of the CK1 enzyme family. The research, led by Sierra Cullati, a postdoc in the Gould lab, and… Read More

    May. 5, 2022

  • Vanderbilt University

    Vanderbilt researchers develop new evolutionary approach for identifying proteins that functionally interact

    Jacob Steenwyk, a graduate student in biological sciences, and collaborators at Vanderbilt, Tel Aviv University and University of Wisconsin-Madison measured the coevolution of pairs of genes shared across budding yeasts to identify the genes that participate in the same cellular or molecular functions.  The results of this work… Read More

    May. 5, 2022