Stephen Doster
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Study sheds light on the dark side of obesity
Obesity is an inflammatory condition that can damage tissues throughout the body, resulting in increased risk for cardiovascular disease, insulin resistance, type 2 diabetes and possibly kidney disease. The agents of inflammation are immune cells called macrophages, which accumulate in fatty tissue, and which produce inflammatory chemicals called cytokines. But… Read MoreMay. 17, 2022
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Collaborative research yields new protein structure
Structure of a caveolin-1 complex obtained using cryo-electron microscopy. A protomer, or a structural unit, is highlighted in magenta. The image was cropped to focus on panel A of Figure 1 of the paper, modified and published here in accordance to a CC BY-NC 4.0 license. Read MoreMay. 16, 2022
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Vanderbilt University honors emeritus and emerita faculty
Vanderbilt University has honored 35 retiring faculty members for their years of service by bestowing upon them the title of emerita or emeritus faculty. They were recognized during Vanderbilt’s Commencement ceremony on May 13. A faculty member who has served the university with distinction over a period of years and… Read MoreMay. 13, 2022
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Resistance to COVID-19 drug detected in lab study
The virus that causes COVID-19 can develop partial resistance to the antiviral drug remdesivir during infection of cultured cells in the laboratory by more than one mechanism. The results of the laboratory study led by researchers at Vanderbilt University Medical Center and published April 28 in the journal Science… Read MoreMay. 12, 2022
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Resistance to COVID-19 drug detected in lab study
The virus that causes COVID-19 can develop partial resistance to the antiviral drug remdesivir during infection of cultured cells in the laboratory by more than one mechanism. The results of the laboratory study led by researchers at Vanderbilt University Medical Center and published April 28 in the journal Science… Read MoreMay. 12, 2022
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Six biomedical Ph.D. students awarded prestigious NSF Graduate Research Fellowships
From left to right, top to bottom: Minna Apostolova, Blake Baleami, Andreanna Burman, Drew Dixson, Kevin McCarty, Teresa Piedad Torres, Jose Zepeda, Kaeli Bryant, Julissa Burgos, Heather Hartmann, Reese Martin, Zach Sanchez. By Emily Overway The National Science Foundation Graduate Research Fellowship Program… Read MoreMay. 10, 2022
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Cryo-EM reveals the molecular mechanism of IP3 receptor channel opening
Research led by co-first authors Emily Schmitz, a graduate student in the Chemical and Physical Biology program, and Hirohide Takahashi, a research instructor in molecular physiology and biophysics, identified the structure of the human type-3 inositol 1,4,5-triphosphate, or IP3, receptor in several conformations using cryo-electron microscopy. Schmitz and Takahasi, who… Read MoreMay. 9, 2022
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Researchers investigate self-regulation of an enzyme with critical cellular functions
he lab of Kathy Gould, Louise B. McGavock Professor and professor of cell and developmental biology, used a multi-disciplinary approach that included structural biology, biochemistry, and molecular biology to investigate the regulation of the CK1 enzyme family. The research, led by Sierra Cullati, a postdoc in the Gould lab, and… Read MoreMay. 5, 2022
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Vanderbilt researchers develop new evolutionary approach for identifying proteins that functionally interact
Jacob Steenwyk, a graduate student in biological sciences, and collaborators at Vanderbilt, Tel Aviv University and University of Wisconsin-Madison measured the coevolution of pairs of genes shared across budding yeasts to identify the genes that participate in the same cellular or molecular functions. The results of this work… Read MoreMay. 5, 2022
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Faculty awards honor teaching, clinical, research excellence
The 2022 Vanderbilt University School of Medicine Academic Enterprise Awards for Excellence in Teaching, Extraordinary Performance of Clinical Service, and Outstanding Contributions to Research were presented April 29 during the annual spring faculty meeting. The recipients include…… Read MoreMay. 5, 2022