Stephen Doster
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CD40 expression correlates with response to immunotherapy in melanoma patients
L-R: Ann Richmond, Chi Yan By Wendy Bindeman Ann Richmond, professor of pharmacology, and Chi Yan, a research assistant professor in the Richmond lab, recently published a study showing that expression of a protein called CD40 can be used to predict response to immunotherapy in malignant melanoma. Read MoreMar. 1, 2022
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Vanderbilt team discovers potential explanation for treatment resistance in skin cancer
Many melanoma patients are treated with drugs called BRAF or MEK inhibitors that specifically target the mutant proteins created in cancerous tumors. These inhibitors can block the tumors’ ability to grow and spread. According to Ann Richmond, Ingram Professor of Cancer Research and professor of pharmacology… Read MoreFeb. 28, 2022
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Experts to discuss what comes next in the COVID-19 pandemic
Registration is now open for a special panel discussion about the future of COVID-19, featuring some of Vanderbilt University’s leading experts in COVID vaccines, infectious disease and public health. The virtual discussion, “The COVID Conundrum: What’s Next,” will be Thursday, March 10, at noon CT. Panelists… Read MoreFeb. 25, 2022
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Researchers find clue to drug-induced arrhythmias
Researchers at Vanderbilt University Medical Center have made a fundamental discovery about how the heart compensates for genetic variations that otherwise could trigger abnormal and potentially fatal heart rhythms. Their findings, reported recently in the journal Circulation, add significantly to understanding what causes abnormal heart rhythms, or arrhythmias, and… Read MoreFeb. 25, 2022
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Melanoma treatment response
Although targeted therapies have been developed for melanoma patients, tumor progression eventually results. Understanding characteristics of melanoma associated with treatment resistance is important for prolonging therapy effectiveness. In a retrospective study of patients treated with BRAF and/or MEK inhibitors, Chi Yan, PhD, Ann Richmond, PhD, and… Read MoreFeb. 25, 2022
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Vanderbilt inks collaboration with precision neuroscience company Neumora to continue development of investigational treatment for neuropsychiatric disorders
Vanderbilt University has signed an exclusive, worldwide license and a research collaboration agreement with Neumora Therapeutics, Inc., a clinical-stage biotechnology company pioneering precision medicines for brain diseases through the integration of data science and neuroscience. The licensed program centers around the M4 muscarinic receptor positive allosteric modulator—including… Read MoreFeb. 23, 2022
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Student-led research creates a publicly available mitogenomic data source for a human pathogen
Publicly available data sources help drive progress in science, especially complete and annotated data sources. As part of a student research project, corresponding author Anne Hatmaker, a Ph.D. student in the lab of Antonis Rokas, professor of biological sciences, and first author Miya Hugaboom, an undergraduate in the Rokas lab,… Read MoreFeb. 21, 2022
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‘Black Excellence in Research and the Future of Diversity in Academia’ virtual event
In recognition of Black History Month, the School of Medicine Basic Sciences’ monthly virtual Lab-to-Table Conversation will celebrate Black excellence in research and discuss the future of diversity in academia. The event will take place on Tuesday, Feb. 22, from noon to 1 p.m. CT. The discussion is free and… Read MoreFeb. 18, 2022
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Understanding the molecules and brain circuits recruited by stressful experience
Stressful experiences can lead to adaptive or detrimental behaviors. Understanding how stress can affect our brains can help understand basic brain function and is also essential to discerning causes and treatments for some diseases. A group of researchers led by Jeffrey Conn, professor of pharmacology at… Read MoreFeb. 18, 2022
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Richard Sando awarded 2022 Sloan Research Fellowship in neuroscience
Richard Sando, assistant professor of pharmacology, has been selected to receive a 2022 Sloan Research Fellowship, one of the most competitive and prestigious awards available to early-career researchers. The fellowships, awarded annually by the Alfred P. Sloan Foundation, honor extraordinary U.S. and Canadian scientists and scholars… Read MoreFeb. 16, 2022