Stephen Doster
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A “torque” for tumor blood vessels
Aug. 20, 2020, 9:30 AM by Bill Snyder Tumors tend to have leaky and highly dysfunctional blood vessels that can prevent anti-cancer drugs and immune cells from getting to them. Improving the effectiveness of cancer therapy, therefore, may require finding ways to “normalize” tumor blood vessels. Signaling through a protein… Read MoreAug. 20, 2020
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‘Scavenger’ molecule may point to new atherosclerosis treatment
Aug. 20, 2020, 8:48 AM From left, Huan Tao, MD, PhD, Sean Davies, PhD, Jiansheng Huang, PhD, and MacRae Linton, MD, led the study that identified a potential new treatment for atherosclerosis. (photo by Donn Jones) by Bill Snyder A small-molecule “scavenger” that reduces inflammation and formation of atherosclerotic plaque… Read MoreAug. 20, 2020
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Discovery of natural compound may help fend off antibiotic resistance of hard-to-treat infections
by Marissa Shapiro Aug. 19, 2020, 12:00 PM The Vanderbilt Laboratory for Biosynthetic Studies, led by Brian Bachmann, professor of chemistry, has discovered a naturally occurring compound that is resilient to antibiotic resistance because of its rare properties. Antibiotic resistance, the ability of… Read MoreAug. 20, 2020
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A potential new targeted therapy for metastatic melanoma
By Wendy Bindeman https://cdn.vanderbilt.edu/t2-main/medschool-prd/wp-content/uploads/sites/101/2020/08/Discovery_Richmond-SMWeb-1.mp4 Melanoma is the most common of all cancers. The American Cancer Society estimates that over 100,000 new melanomas will be diagnosed in the U.S. in 2020. While 60 percent of people with metastatic melanoma, an aggressive type of skin cancer, have multiple treatment options… Read MoreAug. 19, 2020
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Vanderbilt University School of Medicine Basic Sciences announces eight new additions to its Board of Visitors
By Zoe Weinman The Board of Visitors of Vanderbilt University School of Medicine Basic Sciences, established in 2018, recently added eight new members. The board consists of alumni and non-alumni who have expertise in fields related to basic sciences research, education and career development. These experts act as advisors to… Read MoreAug. 19, 2020
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The importance of estrogen cycles
Aug. 6, 2020, 10:00 AM by Sarah Glass Oral contraceptives are implicated in slightly increasing breast cancer risk. This birth control method contains forms of estrogen, a hormone that binds ERalpha (estrogen receptor alpha), to alter the reproductive cycle. While much is known about estrogen signaling, few have researched how receptor homeostasis… Read MoreAug. 6, 2020
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Understanding sex-based behaviors may improve psychiatric treatments
By Sara Eaton There are biological differences in how male and female mice respond to different cues in their environment. Deciphering those differences can help researchers develop drugs that work equally well in both human sexes. New research from the labs of Erin Calipari and Cody Siciliano, both… Read MoreAug. 5, 2020
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Siciliano wins Fay/Frank Seed Grant and Alkermes Pathways Research Award
Aug. 5, 2020, 7:00 AM By Jenna Somers Cody Siciliano (Vanderbilt University) Assistant Professor of Pharmacology Cody Siciliano has been awarded the Fay/Frank Seed Grant from the Brain Research Foundation and the Alkermes Pathways Research Award from the… Read MoreAug. 5, 2020
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Protein study may be key to treating fibrotic diseases
Jul. 30, 2020, 8:08 AM by Bill Snyder A protein linked to amyotrophic lateral sclerosis (ALS), a progressive neurological disease that causes muscle weakness, may be a key to treating fibrotic disease of the kidneys and other organs, researchers at Vanderbilt University Medical Center reported recently. FUS is the… Read MoreJul. 31, 2020
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Discovery of a brain ‘negative regulator’ alters understanding of brain function and potential treatment of cognitive disorders
by Marissa Shapiro Jul. 21, 2020, 10:00 AM The brain has an uncanny ability to enhance or reduce communication between brain cells. Whether or not communication is fast or slow changes the brain’s overall function. Understanding how these cells communicate within the brain is… Read MoreJul. 23, 2020