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Doug Kojetin, associate professor of biochemistry, and a collaborator from the Guangzhou Laboratory, use NMR and crystallography to elucidate the binding pose of GW9662 and T0070907 cobound with synthetic ligands for the first time. Read More

There's a tendency to view the past as a "failed" state, assuming that evolution drives toward optimization. This isn't necessarily true. There is a vast, complex history we have yet to fully understand—and we should strive to uncover it. Read More

The Center for Extracellular Vesicle Research, which is made up of over 20 laboratories spanning Vanderbilt University, held its annual retreat in late September. Researchers discussed the types of biomolecular cargoes EVs contain and how EVs holding unique cargoes can be used as diagnostic tools. Read More

Polycystic ovarian syndrome  is a complex endocrinological disorder with widespread prevalence, affecting approximately one in ten women worldwide. Treatment for PCOS typically involves extensive lifestyle modification and medications to help manage reproductive symptoms and insulin resistance, but there are no treatments that directly target hyperandrogenism. Because of this, women with PCOS often feel unsatisfied with the quality of their care and are belabored by the changes necessary to live out their daily lives. Read More

By Chuck Sanders When I was 13, my brother Scott (12) and I joined our neighbors Matha (12) and Jay (10) on a trip to their family cottage on the bank of the Allegheny River in western Pennsylvania. I had fantasized about this trip for months; I… Read More

The Chazin lab used a combination of nuclear magnetic resonance spectroscopy, isothermal titration calorimetry, computational modelling, and cell-based techniques are used to interrogate the relationship between NEIL1 and RPA. Read More

Quincy Hall describes the experience of arriving on the West Coast as an out-of-state junior college student: “…that’s where the grit comes from. When you have no food. You’ve got to get your own food. No cafeteria. No study hall. None of that. You find out how to be a dog by yourself.” Read More

Through the ASPIRE on the Road program, the Office of Biomedical Research Education and Training office took 12 biomedical trainees from Vanderbilt University to explore Boston’s small and large biotech companies. Read More

By Chuck Sanders, vice dean of the School of Medicine Basic Sciences and professor of biochemistry Joseph Lee Heywood was acquainted with suffering. Having grown up on the New Hampshire/Massachusetts border, as a young man he made his way west to Iowa in search of opportunity. However, before things could… Read More

The new award celebrates the scientific relationship between  a mentor and trainee pair by providing them with $4,000 to attend a national conference in the trainee's research field. Read More