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Genetic Heterogeneity in Colorectal Cancer Metastases
Genetic Heterogeneity in Colorectal Cancer Metastases Despite recent progress in early diagnosis and treatment, colorectal cancer remains a major cause of morbidity and mortality, with 90% of the deaths attributable to metastatic disease. We now know that cancer is largely a disease of genetic mutations and that most cancers… Read MoreSep. 22, 2017
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Inhibiting obesity
NAPEs, a family of lipid molecules, are produced in the intestinal tract after food intake and exert leptin-like effects: they reduce food intake and weight gain. Given their potential importance in regulating satiety and inhibiting obesity, Sean Davies, Ph.D., and colleagues are exploring NAPE action. Read MoreSep. 22, 2017
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University of Kansas honors Lindsley’s pharmacology research
Craig Lindsley, Ph.D., co-director of the Vanderbilt Center for Neuroscience Drug Discovery, has been honored by the University of Kansas with the 2018 Edward E. Smissman Lectureshipfor his outstanding contributions to the fields of medicinal chemistry and molecular pharmacology. Read MoreSep. 22, 2017
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Grant supports Oates’ research on acetaminophen and stroke
John Oates, M.D., a pioneering clinical pharmacologist at Vanderbilt University Medical Center (VUMC), has been awarded a one-year, $20,000 grant from the Brain Aneurysm Foundation to support studies of the stroke-reducing potential of acetaminophen. Oates is the Thomas F. Frist Sr. Professor of Medicine, professor of Pharmacology and founding director of the Division… Read MoreSep. 22, 2017
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Special symposium to honor Moses’ cancer research contributions
A research symposium honoring the career of Harold (Hal) Moses, M.D., who founded and served as director emeritus of Vanderbilt-Ingram Cancer Center, has been slated for Wednesday, Oct. 11, 7:45 a.m. – 3:30 p.m., at the Vanderbilt Student Life Center. The free symposium will feature a roster of renowned cancer researchers… Read MoreSep. 22, 2017
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A Super-Resolution Look at the Contractile Ring
During cell division, a ring of proteins forms around the equator of the cell. Then, after the chromosomes have been distributed to each pole of the mitotic spindle, the ring constricts, separating the cell into two daughter cells. This contractile ring is a complex structure that uses the mechanical… Read MoreSep. 22, 2017
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Special symposium to honor Moses’ cancer research contributions
A research symposium honoring the career of Harold (Hal) Moses, M.D., who founded and served as director emeritus of Vanderbilt-Ingram Cancer Center, has been slated for Wednesday, Oct. 11, 7:45 a.m. – 3:30 p.m., at the Vanderbilt Student Life Center. The free symposium will feature a roster of renowned cancer researchers… Read MoreSep. 22, 2017
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Excess dietary manganese increases risk of staph infection in heart
Too much dietary manganese — an essential trace mineral found in leafy green vegetables, fruits and nuts — promotes infection of the heart by the bacterium Staphylococcus aureus(“staph”). “The human body does a wonderful job of regulating nutrient levels, and a traditional Western diet has plenty of minerals in it. The idea… Read MoreSep. 22, 2017
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Vanderbilt, Bayer collaborate to develop new therapies against kidney diseases
Vanderbilt University Medical Center (VUMC) and Bayer have agreed on a five-year strategic research alliance to evaluate new drug candidates for the treatment of kidney diseases, with the goal of accelerating the translation of innovative approaches from the laboratory to pre-clinical development. Read MoreSep. 15, 2017
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Trio of Vanderbilt scientists set for Discovery Lecture
Three Vanderbilt University scientists on the forefront of research in cellular dynamics and cancer treatment, including Marija Zanic, Ph.D., assistant professor of Cell and Developmental Biology and Chemical and Biomolecular Engineering, will discuss their cutting-edge investigations during the next Flexner Discovery Lecture : “Cutting-Edge Molecular Tools Drive Basic Science Discovery and Patient Care,” will begin at… Read MoreSep. 15, 2017