Discoveries

An international collaboration led by Vanderbilt researchers has identified a key component in lesions associated with age-related macular degeneration (AMD), a leading cause of blindness in older adults. Read More

In a collaborative effort co-led by teams from Vanderbilt University Medical Center (VUMC) and the University of Michigan, a comprehensive study that integrates multiple analytic approaches has linked a regulatory gene network and functional defects in insulin-producing pancreatic beta cells to Type 2 diabetes. The study, published Dec. 4 in… Read More

A potential schizophrenia treatment discovered through the Warren Center for Neuroscience Drug Discovery has been cleared by the U.S. Food and Drug Administration for use in phase 1 clinical trials—the third WCNDD therapeutic to reach that benchmark.  “Vanderbilt is proud that a discovery by our researchers at the Warren Center… Read More

Researchers at Vanderbilt University Medical Center for the first time have shown that activation of the epidermal growth factor receptor (EGFR) is essential for the development of kidney fibrosis, tissue scarring following injury that can lead to kidney failure. Their discovery, reported Nov. 14 in the journal Nature Communications,… Read More

On Nov. 2, Lisa Monteggia, Barlow Family Director of the Vanderbilt Brain Institute and professor of pharmacology, psychiatry and psychology, joined John Hoomes, CEO and artistic director of the Nashville Opera, for a discussion on the artistic approach and scientific research behind the Nashville Opera’s upcoming performance of The Man Who Mistook His Wife for a Hat. Read More

A new study in the journal Cell Host & Microbe brings the beneficial bacterial residents of the gut into the mix. The findings show that commensal gut microbes impact the host-pathogen competition for iron and have implications for therapeutic strategies aimed at preventing pathogens from acquiring essential nutrients. Postdoctoral fellow Yasiru… Read More

Kimryn Rathmell, MD, PhD, chair of Medicine at Vanderbilt University Medical Center, has received the Paragon Award for Research Excellence from the Doris Duke Foundation (DDF). The award was presented to Rathmell and 24 others who are alumni of the Doris Duke Clinical Scientist Development Awards program during a ceremony… Read More

As cells grow and divide, their DNA needs to be accurately replicated and properly segregated to new cells. Errors during replication or segregation can alter the genome and promote cancer. Now, researchers at Vanderbilt University Medical Center have identified the mechanism by which the enzyme and tumor suppressor SETD2 prevents… Read More

A team of Vanderbilt engineers, biologists and education specialists have received a $3 million grant from the National Science Foundation to advance large-scale biomanufacturing of cell-derived nanoparticles that can deliver precisely targeted drugs to the site of a disease. The grant is part of the NSF’s Future Manufacturing program that is… Read More