Discoveries

  • Vanderbilt University

    Study identifies human proteins with segments devoid of genetic variation

    By Leah Mann Charles Sanders, Ph.D. The lab of Charles Sanders, professor of biochemistry and the Aileen M. Lange and Annie Mary Lyle Chair for Cardiovascular Research, published a study in Protein Science identifying all human proteins that have at least one segment that does not have… Read More

    Jan. 27, 2023

  • Vanderbilt University

    The Expert from Nowhere

    To understand a protein’s structure is to understand its function, says structural and chemical biologist Jens Meiler, PhD, distinguished research professor of Chemistry. It can take a PhD student up to five sleep-deprived years to determine the structure of a single protein, and of the 20,000 human proteins, only about… Read More

    Jan. 26, 2023

  • Headshot of Wenbiao Chen.

    CRISPR screen identifies role for a specific protein in insulin secretion

    By Leah Mann Wenbiao Chen, Ph.D. The labs of Wenbiao Chen, associate professor of molecular physiology and biophysics, and Irina Kaverina, professor of cell and development biology, recently published a study in Molecular Metabolism focused on detecting genes that regulate insulin secretion. The authors demonstrated a new… Read More

    Jan. 25, 2023

  • Vanderbilt University

    Estrada to lead VUSM health equity education

    Lourdes Estrada, PhD, associate professor of Biochemistry, has been named assistant dean for Health Equity Education, Vanderbilt University School of Medicine, effective Feb. 1. In this role, she will work to develop and expand initiatives that integrate core principles of health equity into VUSM’s health sciences educational programs, with an… Read More

    Jan. 19, 2023

  • Vanderbilt University Basic Sciences Jeffrey Rathmell, PhD, has been named to receive a distinguished innovator award from the Lupus Research Alliance.

    Study identifies potential new approach for treating lupus

    Targeting iron metabolism in immune system cells may offer a new approach for treating systemic lupus erythematosus (SLE) — the most common form of the chronic autoimmune disease lupus. A multidisciplinary team of investigators at Vanderbilt University Medical Center has discovered that blocking an iron uptake receptor reduces disease pathology… Read More

    Jan. 19, 2023

  • Vanderbilt University

    New screening method could pave the way for future cancer drug discoveries

    The laboratories of Brian Bachmann, professor of chemistry, biochemistry and pharmacology, and Jonathan Irish, associate professor of cell and developmental biology and pathology, microbiology and immunology, have developed a method to discover new small molecules that may kill cancer cells by working through the body’s immune system. The method is… Read More

    Jan. 18, 2023

  • Vanderbilt University

    Renã Robinson receives National Institutes of Health grant for faculty success program to promote equity in science

    Renã Robinson, Dorothy Wingfield Phillips Chancellor’s Faculty Fellow and professor of chemistry, received $2.04 million in funding from the National Institutes of Health to start a program that will help underrepresented minority faculty further their success in STEM. Collaborators on the grant include researchers from the University of Kentucky and… Read More

    Jan. 18, 2023

  • Vanderbilt University

    Vanderbilt biochemists join international researchers in discovery of the first new antibiotic for urinary tract infections in more than 20 years

    Neil Osheroff, John Coniglio Chair in Biochemistry and professor of biochemistry and medicine, is part of an international research collaboration resulting in what is on track to be the first new antibiotic treatment for uncomplicated urinary tract infections in more than 20 years. “We now have a direct path connecting… Read More

    Jan. 18, 2023

  • Vanderbilt University

    Roden honored for his leadership in precision medicine

    Dan Roden, MD, Senior Vice President for Personalized Medicine at Vanderbilt University Medical Center, will receive the PMWC 2023 Pioneer Award Jan. 27 during this year’s Precision Medicine World Conference. Approximately 2,500 people from more than 30 countries are registered for the three-day meeting, to be held in Santa Clara,… Read More

    Jan. 12, 2023

  • Vanderbilt University

    VUMC researchers upend dogma about vasopressin production

    It’s time to revise the textbook entry for vasopressin production. For 100 years, it has been thought that vasopressin — a hormone that regulates water and blood pressure homeostasis — is only produced in the brain. Now, Vanderbilt University Medical Center investigators have discovered that vasopressin is also produced in… Read More

    Jan. 12, 2023