Research, News & Discoveries

Oct. 13, 2020, 1:44 PM by Bill Snyder AstraZeneca is advancing into phase 3 clinical trials with an investigational COVID-19 therapy of two long-acting antibodies discovered by Vanderbilt University Medical Center and optimized by AstraZeneca. On Oct. 9, AstraZeneca announced it received support from the U.S. government for the development… Read More

For more than a decade Matt Lang and collaborators across the U.S. have worked to recreate key components of T-cells and how they know when to start fighting disease. Conventional wisdom suggested that T-cells formed regular, force-free bonds with infected cells, and in doing so caused the chain reaction of… Read More

Oct. 8, 2020, 10:28 AM Michelle Southard-Smith, PhD, Aaron May-Zhang, PhD, and colleagues have created a molecular ‘atlas’ of genes expressed by the neuronal cells within the intestine that coordinate the functions of the gastrointestinal (GI) tract. (photo by Susan Urmy) by Bill Snyder Researchers at Vanderbilt University Medical Center… Read More

Vanderbilt researchers awarded one of NSF’s 24 new projects to drive future manufacturing One of the challenges of drug delivery systems is to optimize their targeting properties so therapeutic compounds used in smaller amounts reach only a specific area of the body and result in little or no side effects. Read More

by Marissa Shapiro Oct. 6, 2020, 9:00 AM A Vanderbilt team of experts in virology, genetics, structural biology, chemistry, physiology, medicine, immunology and pharmacology have together developed technology to understand and predict animal susceptibility to SARS-CoV-2, the scientific name for the strain of coronavirus… Read More

Oct. 5, 2020, 8:00 AM by Sarah Glass Diabetic patients can develop kidney disease since high levels of glucose damage blood vessels, prompting accumulation of scarred tissue with reduced kidney function. Recent studies have suggested that progressive interstitial fibrosis in the renal proximal tubule is an important mediator in the… Read More

By Kendra H. Oliver See enlarged view of infographic. For many, the virtual work era ushered in by COVID-19 has been exhausting. Discounting stressors related to personal health, public health and politics, an underappreciated source of stress may be mainly related to the enormous increase of… Read More

By Lorena Infante Lara Scott Hiebert, Hortense B. Ingram Chair in Cancer Research and professor of biochemistry, will serve as acting chair for the National Cancer Advisory Board. Originally appointed by President Barack Obama… Read More

Sep. 24, 2020, 9:19 AM by Bill Snyder Cody Siciliano, PhD, assistant professor of Pharmacology in the Vanderbilt University School of Medicine, has been selected to receive a one-year, $100,000 research award from the Stanley Cohen Innovation Fund to support his studies of the neural substrates of… Read More

Sep. 24, 2020, 9:19 AM by Bill Snyder Cody Siciliano, PhD, assistant professor of Pharmacology in the Vanderbilt University School of Medicine, has been selected to receive a one-year, $100,000 research award from the Stanley Cohen Innovation Fund to support his studies of the neural substrates of… Read More