Artificial Intelligence
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Center for Computational Systems Biology explores how 3D AI is reshaping biomedical research
The Center for Computational Systems Biology hosted its inaugural Symposium on AI, Spatial & Systems Biology. The two-day event highlighted how emerging 3D artificial intelligence technologies are transforming biomedical research, ushering in a new era of discovery that bridges molecular, cellular, and systems-level understanding of biology. Read MoreNov. 5, 2025
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Beyond the fold: From single snapshots to shapeshifting proteins
Started in June 2025, a new collaborative science project called diffUSE involving Vanderbilt University, Cornell University, and the University of California, San Francisco, could be the next watershed moment. The $5 million, three-year project led by the Astera Institute will advance our understanding of protein motion. Using diffuse scattering, an overlooked signal measured by X-ray crystallography, the project will determine how protein dynamics are characterized, leading to a new paradigm in dynamic structural biology. Read MoreSep. 25, 2025
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Vanderbilt alumnus Walt Gall applies basic sciences to AI and space innovation
Walt Gall, PhD’02, sat down with us to discuss his experience studying basic science at Vanderbilt and how it played a role in his career. Gall is an entrepreneur in residence at the Exploration Institute. Read MoreJul. 16, 2025
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John M. Jumper, DeepMind researcher and Vanderbilt alumnus, shares 2024 Nobel Prize in chemistry
Dr. Jumper’s work with AlphaFold2 represents an unprecedented step in the integration of artificial intelligence and the natural sciences. John and his colleagues have given us inspiring evidence of its limitless potential for advancing scientific discovery. Read MoreOct. 10, 2024
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Vanderbilt University School of Medicine Basic Sciences adds Carterra’s LSAXT instrument to speed drug and vaccine research and advance patient care
The Center for Structural Biology in the School of Medicine Basic Sciences will be a hub of research innovation using Carterra’s platform in traditional and AI-driven workflows for characterizing both antibodies and other biomolecules Read MoreSep. 25, 2024
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Expert in bio-inspired AI systems visits Vanderbilt to discuss the future potential of neuromorphic supercomputers
At a recent Center for Applied AI in Protein Dynamics seminar, Christian Mayr of Technische Universität Dresden discussed how new hardware technologies will transform AI development and allow machines to mimic the efficiency and processing power of the human brain. Read MoreAug. 26, 2024
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Basic Sciences trainees visit Boston’s biotech with ASPIRE on the Road
Through the ASPIRE on the Road program, the Office of Biomedical Research Education and Training office took 12 biomedical trainees from Vanderbilt University to explore Boston’s small and large biotech companies. Read MoreJul. 11, 2024
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Research Snapshot: Exploring the range of AlphaFold2’s utility within the realm of protein dynamics
Benjamin P. Brown, assistant professor of pharmacology, and colleagues in the departments of molecular physiology and biophysics, pharmacology, and chemistry, have determined that AlphaFold2 can be used to generate approximations of relative conformational preferences of proteins, which will help researchers better understand a protein’s structure and function across a range of conditions and mutational states. Read MoreMay. 9, 2024
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Vanderbilt launches Center for Applied Artificial Intelligence in Protein Dynamics
The School of Medicine Basic Sciences has launched the Center for Applied Artificial Intelligence in Protein Dynamics, which is focused on the intersection of artificial intelligence, machine learning, and macromolecular mechanism. It is helmed by Hassane Mchaourab, who holds the Louise B. McGavock Chair in the Department of Molecular Physiology and Biophysics. Read MoreMar. 7, 2024
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Study finds a role for AI in drug repurposing pipeline
The team prompted the chatbot to review the biomedical research literature and suggest 20 drugs for Alzheimer’s disease, ranking them for potential effectiveness. With a second prompt they asked for confirmation of the initial 20 suggestions. They repeated both prompts 10 times. Read MoreFeb. 27, 2024