Cancer Cells

Researchers in the lab of Vivian Weiss, assistant professor of pathology, microbiology, and immunology, recently published a review article in Cancer Research that describes the role of the Wnt pathway in TAMs and tumor biology. Read More

The laboratories of Brian Bachmann, professor of chemistry, biochemistry and pharmacology, and Jonathan Irish, associate professor of cell and developmental biology and pathology, microbiology and immunology, have developed a method to discover new small molecules that may kill cancer cells by working through the body’s immune system. The method is… Read More

Cancer cells metastasize, or spread to different parts of the body, by escaping from a primary tumor and invading neighboring tissues. To penetrate normal tissue barriers, migrating cancer cells form membrane protrusions called invadopodia that degrade the surrounding extracellular matrix (ECM).  Aron Parekh, PhD, and colleagues… Read More