Pharmacology

Quynh Anh Nguyen has been awarded the highly competitive Klingenstein Fellowship in Neuroscience, a national honor that recognizes promising early-career investigators pursuing high-risk, high-reward research in the neurosciences. The fellowship will support Nguyen’s pioneering investigations into the brain’s inhibitory circuitry and its role in the development and control of epilepsy. Read More

By Lorena Infante Lara Food-related allergies and their effects are insidiously common in the United States: over seven percent of children and over 10 percent of adults are affected.  Although a quarter of people with food allergies have an epinephrine pen, they are expensive and have to be replaced… Read More

A recent review from the pharmacology lab of Valentina Cigliola explores the remarkable regenerative capabilities of zebrafish and neonatal mice and how insights into these mechanisms could pave the way for innovative and regenerative therapies in humans suffering from spinal cord injuries or neurodegenerative diseases. Read More

What makes these results exceptional isn’t just the compounds themselves, it’s what they represent: the value of translational research grounded in real-world therapeutic goals. The partners chose to release these best-in-class tool compounds to the scientific community to accelerate further discovery. Read More

Major depression is one of the most common mental disorders in the U.S. Approximately 7% (17.3 million) of American adults had at least one major depressive episode in 2017. Roughly 10 percent of the U.S. population is afflicted with major depressive disorder at any… Read More

Driven by personal loss, a graduate student and his mentors unveil the mysteries of CFTR mutations, seeking to unlock new treatments for cystic fibrosis patients who currently resist available drugs. Read More

What makes these results exceptional isn’t just the compounds themselves, it’s what they represent: the value of translational research grounded in real-world therapeutic goals. The partners chose to release these best-in-class tool compounds to the scientific community to accelerate further discovery. Read More

In this episode of Quantum Potential, Craig Lindsley, William K. Warren, Jr. Professor of Medicine, University Distinguished Professor of Biochemistry, Chemistry and Pharmacology and executive director of the Warren Center for Neuroscience Drug Discovery, joins Provost C. Cybele Raver to discuss transformative research exploring how subtle tweaks to brain chemistry could change the way we treat neurodegenerative diseases and chronic pain. Lindsley shares how academic-industry collaborations drive innovation in drug discovery and highlights how Vanderbilt’s scientific workflow is enabling the broader research community to build on its breakthroughs. Read More

BrightFocus Foundation’s Alzheimer’s Disease Research program has awarded a three-year, $300,000 research grant to Monica Santisteban, assistant professor of Medicine, Neurology and Pharmacology, to investigate the role of the renin angiotensin system in the progression of Alzheimer’s disease pathology. Read More

For the nearly 30 percent of major depressive disorder patients who are resistant to treatment, ketamine provides some amount of normalcy, but it requires frequent treatment and can have side effects. Vanderbilt researchers now show in proof-of-concept experiments that it may be possible to extend ketamine’s antidepressant effect from about a week to up to two months. Read More