Walter Chazin

Brandt Eichman and Walter Chazin, professors of biochemistry, worked together to provide a better understanding of how exactly DNA replication is initiated. Their work will influence novel small molecule modifier designs that may serve as tools for detailed studies of DNA replication in cells and eventual therapies. Read More

A new study in the journal Cell Host & Microbe brings the beneficial bacterial residents of the gut into the mix. The findings show that commensal gut microbes impact the host-pathogen competition for iron and have implications for therapeutic strategies aimed at preventing pathogens from acquiring essential nutrients. Postdoctoral fellow Yasiru… Read More

Vanderbilt researchers have developed an active machine learning approach to predict the effects of tumor variants of unknown significance, or VUS, on sensitivity to chemotherapy. VUS, mutated bits of DNA with unknown impacts on cancer risk, are constantly being identified. The growing number of rare VUS makes it imperative for… Read More