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  • Vanderbilt University

    Faculty Appointment: Jason MacGurn, Ph.D.

    I am very pleased to announce the appointment of Jason MacGurn, Ph.D., to the rank of Assistant Professor of Cell and Developmental Biology on the tenure track, effective August 1, 2013. Jason is currently a Post Doctoral Fellow in Scott Emr’s Lab at Cornell University Weill Institute for Cell and… Read More

    Jul. 8, 2013

  • Vanderbilt University

    Lab Publication: Insights into the mitotic phosphoproteome

    Mol Cell Proteomics. 2013 May;12(5):1074-86. doi: 10.1074/mcp.M112.025924. Epub 2013 Jan 7. Comprehensive proteomics analysis reveals new substrates and regulators of the fission yeast clp1/cdc14 phosphatase. Chen JS, Broadus MR, McLean JR, Feoktistova A, Ren L, Gould KL.   ‡Howard Hughes Medical Institute and Department of Cell and Developmental… Read More

    Jun. 3, 2013

  • Vanderbilt University

    Publication: Scribble implicated in control of vesicle traffic

    The Scribble polarity protein stabilizes E-cadherin/p120-catenin binding and blocks retrieval of E-cadherin to the Golgi. Lohia M, Qin Y, Macara IG. Source Department of Microbiology, Ctr for Cell Signaling, University of Virginia School of Medicine, Charlottesville, VA, USA. Abstract Several polarity proteins, including Scribble (Scrb) have been implicated… Read More

    Apr. 4, 2013

  • Vanderbilt University

    Student Publication: Asunder promotes dynein recruitment

    Jodoin JN, Shboul M, Sitaram P, Zein-Sabatto H, Reversade B, Lee E, Lee LA. Department of Cell and Developmental Biology, Vanderbilt University Medical Center, Nashville, TN 37232-8240, USA. Abstract Recruitment of dynein motors to the nuclear surface is an essential step for nucleus-centrosome coupling in prophase. In cultured human cells,… Read More

    Apr. 3, 2013

  • Faculty Appointment: Ken Lau, Ph.D.

    Faculty Appointment: Ken Lau, Ph.D.

    Cell & Developmental Biology welcomes new faculty member Ken Lau, Ph.D. Dr. Ken Lau comes to Vanderbilt after completing his post postdoctorate training in the laboratory of Kenvi Hargis, Ph.D. In the Molecular Pathology Unit at the Massachusetts General Hospital and Harvard Medical School. Dr. Lau was chosen to join… Read More

    Mar. 21, 2013

  • Vanderbilt University

    CDB Announces Mary Heath as new Department Administrator

    Ian G. Macara, Ph.D. Louise B. McGavock and Chair, Department of Cell and Developmental Biology Vanderbilt University Medical School Mary Heath, MBA, CFA, CRA, will assume the position of Departmental Administrator in the Department of Cell and Developmental Biology on April 22, 2013. Ms. Heath will be… Read More

    Mar. 21, 2013

  • Vanderbilt University

    Morphological and neurochemical comparisons between pulvinar and V1 projections to V2

    Morphological and neurochemical comparisons between pulvinar and V1 projections to V2 Roan Marion1, Keji Li2, Gopathy Purushothaman3, Yaoguang Jiang2 andVivien A. Casagrande1 Article first published online: 22 JAN 2013 DOI: 10.1002/cne.23203 Abstract The flow of visual information is clear at the earliest stages: the retina provides… Read More

    Jan. 22, 2013

  • Loss of the par3 polarity protein promotes breast tumorigenesis and metastasis.

    Loss of the par3 polarity protein promotes breast tumorigenesis and metastasis.

    McCaffrey LM, Montalbano J, Mihai C, Macara IG. Rosalind and Morris Goodman Cancer Research Centre, Department of Oncology, McGill University, Montreal H3A 1A3, Canada. Electronic address: luke.mccaffrey@mcgill.ca. Abstract Loss of epithelial organization is a hallmark of carcinomas, but whether polarity regulates tumor growth and metastasis is poorly understood. To… Read More

    Nov. 23, 2012

  • Cytokinetic regulation of cell polarity

    Cytokinetic regulation of cell polarity

    The rod-shaped fission yeast Schizosaccharomyces pombe, which undergoes cycles of monopolar-to-bipolar tip growth, is an attractive organism for studying cell-cycle regulation of polarity establishment. While previous research has described factors mediating this process from interphase cell tips, we found that division site signaling also impacts the re-establishment of bipolar cell… Read More

    Nov. 23, 2012

  • Spatial regulation of a cell cycle phosphatase

    Spatial regulation of a cell cycle phosphatase

    The rod-shaped fission yeast Schizosaccharomyces pombe, which undergoes cycles of monopolar-to-bipolar tip growth, is an attractive organism for studying cell-cycle regulation of polarity establishment. While previous research has described factors mediating this process from interphase cell tips, we found that division site signaling also impacts the re-establishment of bipolar cell… Read More

    Nov. 23, 2012