Policy on Guarantees
VGER staff are highly experienced. However, outcomes can be affected by many factors, some of which are outside our control. For this reason, we cannot guarantee that any given project will work. For instance, mice are very sensitive to their physical environment, with noise and vibration being known to affect reproductive success and pup survival. Control of these variables lies with the Department of Animal Care (DAC) and is not the responsibility of VGER.
Investigators must assume risk for off-target mutations, random insertions, or mutations in the DNA sequence introduced during commercial synthesis or during integration into the genome.
The Vanderbilt Genome Editing Resource will repeat specific experiments as necessary to achieve the deliverables that have been specified for each service type. However, any additional service beyond that specified for each service type must be approved by the VGER Director.
Adding new mutations to a pre-existing line
VGER is willing to utilize an established mouse line that contains preexisting mutations but doing so adds complexity and cost. Please discuss with the VGER manager.
Authentication of key biological and/or chemical resources
The responsibility for authenticating the mice generated by VGER lies with users.